The association between mean platelet volume and inflammation in geriatric patients with emergency hypertension

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dc.contributor.authorGökdemir, Mehmet Tahir
dc.contributor.authorGökdemir, Gül Şahika
dc.contributor.authorTas, Mahmut
dc.date.accessioned2022-03-02T12:24:14Z
dc.date.available2022-03-02T12:24:14Z
dc.date.issued2019en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Fizyoloji Ana Bilim Dalıen_US
dc.description.abstractObjectives: We aimed to investigate the role of inflammation parameters and platelet activation in geriatric patients with hypertension. Therefore, we compared the levels of those parameters in patients with hypertensive urgency and emergency. We also investigated the potential relationship between those parameters. Methods: Ninety-six hypertensive (HT) patients (aged > 60) were included in the study in two groups: HT emergency (N = 48, group 1) and HT urgency (N = 48, group 2). Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR) and high-sensitive C reactive protein (hs-CRP) were compared between those groups. Optimum cut-off levels of each parameter were determined by the use of Receiver operating characteristic (ROC) curve analysis. Pearson correlation test was used to examine the relationship between variables. Results: The mean MPV and hs-CRP levels were significantly higher in patients with HT emergencies (both P < 0.001). Mean NLR was also significantly different between the two groups (P = 0.011). Pearson correlation analysis revealed a positive but weak correlation between the MPV and NLR (r = 0.245, P = 0.016), the hs-CRP level (r = 0.394, P < 0.001), and the WBC count (r = 0.362, P < 0.001). Conclusion: Increased platelet activity and inflammation are associated with the end organ failure. Levels of MPV and other inflammatory parameters may be useful in the management of geriatric patients with HT. © 2018 The Emergency Medicine Association of Turkeyen_US
dc.identifier.citationGökdemir, M. T., Gökdemir, G. Ş. ve Tas, M. (2019). The association between mean platelet volume and inflammation in geriatric patients with emergency hypertension. Turkish Journal of Emergency Medicine, 19(1), 16-20.en_US
dc.identifier.doi10.1016/j.tjem.2018.03.003
dc.identifier.endpage20en_US
dc.identifier.issn2452-2473
dc.identifier.issue1en_US
dc.identifier.pmid30793060
dc.identifier.scopus2-s2.0-85044514803
dc.identifier.scopusqualityQ2
dc.identifier.startpage16en_US
dc.identifier.trdizinid532193
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S245224731830030X?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/9298
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/532193
dc.identifier.volume19en_US
dc.identifier.wosWOS:000458176800003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherEmergency Medicine Association of Turkeyen_US
dc.relation.ispartofTurkish Journal of Emergency Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHigh-sensitive C reactive proteinen_US
dc.subjectHypertensive emergencyen_US
dc.subjectMean platelet volumeen_US
dc.titleThe association between mean platelet volume and inflammation in geriatric patients with emergency hypertensionen_US
dc.titleThe association between mean platelet volume and inflammation in geriatric patients with emergency hypertension
dc.typeArticleen_US

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