The association between mean platelet volume and inflammation in geriatric patients with emergency hypertension
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Emergency Medicine Association of Turkey
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: We aimed to investigate the role of inflammation parameters and platelet activation in geriatric patients with hypertension. Therefore, we compared the levels of those parameters in patients with hypertensive urgency and emergency. We also investigated the potential relationship between those parameters. Methods: Ninety-six hypertensive (HT) patients (aged > 60) were included in the study in two groups: HT emergency (N = 48, group 1) and HT urgency (N = 48, group 2). Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR) and high-sensitive C reactive protein (hs-CRP) were compared between those groups. Optimum cut-off levels of each parameter were determined by the use of Receiver operating characteristic (ROC) curve analysis. Pearson correlation test was used to examine the relationship between variables. Results: The mean MPV and hs-CRP levels were significantly higher in patients with HT emergencies (both P < 0.001). Mean NLR was also significantly different between the two groups (P = 0.011). Pearson correlation analysis revealed a positive but weak correlation between the MPV and NLR (r = 0.245, P = 0.016), the hs-CRP level (r = 0.394, P < 0.001), and the WBC count (r = 0.362, P < 0.001). Conclusion: Increased platelet activity and inflammation are associated with the end organ failure. Levels of MPV and other inflammatory parameters may be useful in the management of geriatric patients with HT. © 2018 The Emergency Medicine Association of Turkey
Açıklama
Anahtar Kelimeler
High-sensitive C reactive protein, Hypertensive emergency, Mean platelet volume
Kaynak
Turkish Journal of Emergency Medicine
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
19
Sayı
1
Künye
Gökdemir, M. T., Gökdemir, G. Ş. ve Tas, M. (2019). The association between mean platelet volume and inflammation in geriatric patients with emergency hypertension. Turkish Journal of Emergency Medicine, 19(1), 16-20.
