The association between mean platelet volume and inflammation in geriatric patients with emergency hypertension

Yükleniyor...
Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Emergency Medicine Association of Turkey

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objectives: We aimed to investigate the role of inflammation parameters and platelet activation in geriatric patients with hypertension. Therefore, we compared the levels of those parameters in patients with hypertensive urgency and emergency. We also investigated the potential relationship between those parameters. Methods: Ninety-six hypertensive (HT) patients (aged > 60) were included in the study in two groups: HT emergency (N = 48, group 1) and HT urgency (N = 48, group 2). Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR) and high-sensitive C reactive protein (hs-CRP) were compared between those groups. Optimum cut-off levels of each parameter were determined by the use of Receiver operating characteristic (ROC) curve analysis. Pearson correlation test was used to examine the relationship between variables. Results: The mean MPV and hs-CRP levels were significantly higher in patients with HT emergencies (both P < 0.001). Mean NLR was also significantly different between the two groups (P = 0.011). Pearson correlation analysis revealed a positive but weak correlation between the MPV and NLR (r = 0.245, P = 0.016), the hs-CRP level (r = 0.394, P < 0.001), and the WBC count (r = 0.362, P < 0.001). Conclusion: Increased platelet activity and inflammation are associated with the end organ failure. Levels of MPV and other inflammatory parameters may be useful in the management of geriatric patients with HT. © 2018 The Emergency Medicine Association of Turkey

Açıklama

Anahtar Kelimeler

High-sensitive C reactive protein, Hypertensive emergency, Mean platelet volume

Kaynak

Turkish Journal of Emergency Medicine

WoS Q Değeri

N/A

Scopus Q Değeri

Q2

Cilt

19

Sayı

1

Künye

Gökdemir, M. T., Gökdemir, G. Ş. ve Tas, M. (2019). The association between mean platelet volume and inflammation in geriatric patients with emergency hypertension. Turkish Journal of Emergency Medicine, 19(1), 16-20.