The association between platelet/lymphocyte ratio and coronary artery disease severity

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dc.authorid0000-0003-2434-6690en_US
dc.authorid0000-0002-2145-9406en_US
dc.authorid0000-0002-1992-7848en_US
dc.authorid0000-0003-4326-6418en_US
dc.authorid0000-0002-5090-7247en_US
dc.contributor.authorYüksel, Murat
dc.contributor.authorYıldız, Abdulkadir
dc.contributor.authorOylumlu, Mustafa
dc.contributor.authorAkyüz, Abdurrahman
dc.contributor.authorAydın, Mesut
dc.contributor.authorKaya, Hasan
dc.contributor.authorAcet, Halit
dc.contributor.authorPolat, Nihat
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorAlan, Sait
dc.date.accessioned2022-04-06T07:16:30Z
dc.date.available2022-04-06T07:16:30Z
dc.date.issued2015en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.descriptionPMID: 25550173
dc.description.abstractObjective: In this study, we aimed to explore the association between platelet-to-lymphocyte ratio (PLR) and the severity of atherosclerosis in coronary artery disease (CAD). Methods: Clinical and laboratory data of 388 patients who underwent coronary angiography were evaluated retrospectively. Gensini score, which indicates the severity of atherosclerosis, was calculated for all of the patients. Patients with CAD were categorized as mild and severe atherosclerosis, according to their Gensini score. Eighty patients with normal coronary arteries formed the control group. Mean PLR values of the three study groups were compared. Also, PLR value was tested for whether it showed a positive correlation with Gensini score. Results: The mean PLR of the severe atherosclerosis group was significantly higher than that of the mild atherosclerosis and controls groups (p<0.001). Also, PLR was positively correlated with Gensini score in CAD patients. A cut-off value of 111 for PLR predicted severe atherosclerosis with 61% sensitivity and 59% specificity. Pre-procedural PLR level was found to be independently associated with Gensini score, together with WBC, age, and low HDL level, in the multivariate analysis. Conclusion: Our study suggests that high PLR appears to be additive to conventional risk factors and commonly used biomarkers in predicting severe atherosclerosis. (Anatol J Cardiol 2015; 15: 640-7).en_US
dc.identifier.citationYüksel, M., Yıldız, A., Oylumlu, M., Akyüz, A., Aydın, M., Kaya, H. ve diğerleri. (2015). The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology, 15(8), 640-647.en_US
dc.identifier.doi10.5152/akd.2014.5565
dc.identifier.endpage647en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue8en_US
dc.identifier.pmid25550173
dc.identifier.scopus2-s2.0-84988530087
dc.identifier.scopusqualityQ3
dc.identifier.startpage640en_US
dc.identifier.trdizinid178015
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TVRjNE1ERTFOUT09
dc.identifier.urihttps://hdl.handle.net/11468/9537
dc.identifier.volume15en_US
dc.identifier.wosWOS:000360292000010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorYüksel, Murat
dc.institutionauthorYıldız, Abdulkadir
dc.institutionauthorOylumlu, Mustafa
dc.institutionauthorAkyüz, Abdurrahman
dc.institutionauthorAydın, Mesut
dc.institutionauthorKaya, Hasan
dc.institutionauthorAcet, Halit
dc.institutionauthorPolat, Nihat
dc.institutionauthorBilik, Mehmet Zihni
dc.institutionauthorAlan, Sait
dc.language.isoenen_US
dc.publisherTurkish Society of Cardiologyen_US
dc.relation.ispartofThe Anatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectGensini scoreen_US
dc.subjectPlatelet-lymphocyte ratioen_US
dc.titleThe association between platelet/lymphocyte ratio and coronary artery disease severityen_US
dc.titleThe association between platelet/lymphocyte ratio and coronary artery disease severity
dc.typeArticleen_US

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