In vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey

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dc.authorid0000-0003-4577-4475en_US
dc.authorid0000-0001-6898-7516en_US
dc.authorid0000-0002-2730-5790en_US
dc.authorid0000-0002-1173-5286en_US
dc.contributor.authorTekin, Alicem
dc.contributor.authorDal, Tuba
dc.contributor.authorDeveci, Özcan
dc.contributor.authorTekin, Recep
dc.contributor.authorÖzcan, Nida
dc.contributor.authorAtmaca, Selahattin
dc.contributor.authorDayan, Saim
dc.date.accessioned2023-10-26T11:56:35Z
dc.date.available2023-10-26T11:56:35Z
dc.date.issued2014en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalıen_US
dc.description.abstractStaphylococcus species are one of the major causes of bacterial bloodstream infections. Multi-resistant staphylococci infections are major therapeutic problems. This study was aimed to detect methicillin, linezolid and vancomycin susceptibilities of Staphylococcus isolates. A total of 870 Staphylococcus strains isolated from blood cultures of hospitalized patients with BSI. Antimicrobial susceptibilities of methicillin, linezolid and vancomycin were detected according to the Clinical and Laboratory Standards Institute (CLSI). A total of 771 (88.6%) isolates were coagulase-negative staphylococci (CoNS). 700 (80.5%) isolates were methicillin-resistant (MR) and 170 (19.5%) were methicillin-susceptible (MS). All the MS isolates were also susceptible to linezolid. However 15 (1.7%) of MR strains were resistant to linezolid. The minimum inhibitory concentration range for the linezolid-resistant isolates by Etest was 6-32 µg/mL. The difference between linezolid susceptibilities for MS and MR staphylococci was not quite statistically significant (p = 0.052). There was no statistically significant difference between S. aureus and CoNS isolates for linezolid susceptibility. All of the isolates were susceptible to vancomycin. In conclusion, linezolid is currently an efficient option for the treatment of methicillin-resistant staphylococci infections.en_US
dc.identifier.citationTekin, A., Dal, T., Deveci, Ö., Tekin, R., Özcan, N., Atmaca, S. ve diğerleri. (2014). In vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey. Brazilian Journal of Microbiology, 45(3), 829-833.en_US
dc.identifier.doi10.1590/S1517-83822014000300010
dc.identifier.endpage833en_US
dc.identifier.issn1517-8382
dc.identifier.issue3en_US
dc.identifier.pmid25477914
dc.identifier.scopus2-s2.0-84909947753
dc.identifier.scopusqualityQ3
dc.identifier.startpage829en_US
dc.identifier.urihttps://www.scielo.br/j/bjm/a/JBcWY4hCjm8W6BbxFXKk4sh/?lang=en
dc.identifier.urihttps://hdl.handle.net/11468/12957
dc.identifier.volume45en_US
dc.identifier.wosWOS:000347079600010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTekin, Alicem
dc.institutionauthorDal, Tuba
dc.institutionauthorDeveci, Özcan
dc.institutionauthorTekin, Recep
dc.institutionauthorÖzcan, Nida
dc.institutionauthorAtmaca, Selahattin
dc.institutionauthorDayan, Saim
dc.language.isoenen_US
dc.publisherSociedade Brasileira de Microbiologiaen_US
dc.relation.ispartofBrazilian Journal of Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLinezoliden_US
dc.subjectMethicillinen_US
dc.subjectStaphylococcusen_US
dc.subjectVancomycinen_US
dc.titleIn vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkeyen_US
dc.titleIn vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey
dc.typeArticleen_US

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