Vascular effects of continuous hyperbaric oxygen exposure: experimental outlook

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dc.authorid0000-0003-0044-9476en_US
dc.contributor.authorYavuz, Celal
dc.contributor.authorKarahan, Oğuz
dc.contributor.authorAkkaya, Özgür
dc.date.accessioned2023-10-20T06:23:04Z
dc.date.available2023-10-20T06:23:04Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalıen_US
dc.description.abstractHyperbaric oxygen (HBO) treatment aims to restore tissue oxygenation by inhaling 100% oxygen in pressure rooms. Although beneficial effects have been reported with regard to re-oxygenated ischemic tissues, conflicting findings have been presented concerning the paradoxical tissue response following reperfusion and/or the different responses of non-ischemic normal tissues to increased oxygen exposure. The present study sought to experimentally investigate the impact of continuous HBO treatments on normal aortic tissue. New Zealand rabbits were placed in pressure rooms for 90 minutes per day under 2.5 atmospheric pressure and exposed to HBO for 28 days. Normal structural histology was obtained in the control group. Foam cells were detected in the aortic intimae, thickening and undulation were visualized in the endothelium, and localized separations were observed in the tunica media in the study group compared with the control group. Moreover, salient vasa vasorum was detected in the study group via histopathology. These findings suggest that continuous HBO exposures disrupt the normal vascular structure of a healthy aorta.en_US
dc.identifier.citationYavuz, C., Karahan, O. ve Akkaya, Ö. (2023). Vascular effects of continuous hyperbaric oxygen exposure: experimental outlook. Medical Gas Research, 13(4), 198-201.en_US
dc.identifier.doi10.4103/2045-9912.345175
dc.identifier.endpage201en_US
dc.identifier.issn2045-9912
dc.identifier.issue4en_US
dc.identifier.pmid37077118
dc.identifier.scopus2-s2.0-85152980045
dc.identifier.scopusqualityQ2
dc.identifier.startpage198en_US
dc.identifier.urihttps://journals.lww.com/mgar/fulltext/2023/13040/vascular_effects_of_continuous_hyperbaric_oxygen.8.aspx
dc.identifier.urihttps://hdl.handle.net/11468/12890
dc.identifier.volume13en_US
dc.identifier.wosWOS:001009682600008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYavuz, Celal
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofMedical Gas Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAortaen_US
dc.subjectHealthy tissueen_US
dc.subjectHistopathologyen_US
dc.subjectHyperbaric oxygenen_US
dc.subjectIncreased oxygen exposureen_US
dc.subjectPeriodical treatmenten_US
dc.subjectVascular damageen_US
dc.titleVascular effects of continuous hyperbaric oxygen exposure: experimental outlooken_US
dc.titleVascular effects of continuous hyperbaric oxygen exposure: experimental outlook
dc.typeArticleen_US

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