Vascular effects of continuous hyperbaric oxygen exposure: experimental outlook
Yükleniyor...
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wolters Kluwer Medknow Publications
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Hyperbaric oxygen (HBO) treatment aims to restore tissue oxygenation by inhaling 100% oxygen in pressure rooms. Although beneficial
effects have been reported with regard to re-oxygenated ischemic tissues, conflicting findings have been presented concerning the paradoxical tissue response following reperfusion and/or the different responses of non-ischemic normal tissues to increased oxygen exposure. The
present study sought to experimentally investigate the impact of continuous HBO treatments on normal aortic tissue. New Zealand rabbits
were placed in pressure rooms for 90 minutes per day under 2.5 atmospheric pressure and exposed to HBO for 28 days. Normal structural
histology was obtained in the control group. Foam cells were detected in the aortic intimae, thickening and undulation were visualized in the
endothelium, and localized separations were observed in the tunica media in the study group compared with the control group. Moreover,
salient vasa vasorum was detected in the study group via histopathology. These findings suggest that continuous HBO exposures disrupt the
normal vascular structure of a healthy aorta.
Açıklama
Anahtar Kelimeler
Aorta, Healthy tissue, Histopathology, Hyperbaric oxygen, Increased oxygen exposure, Periodical treatment, Vascular damage
Kaynak
Medical Gas Research
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
13
Sayı
4
Künye
Yavuz, C., Karahan, O. ve Akkaya, Ö. (2023). Vascular effects of continuous hyperbaric oxygen exposure: experimental outlook. Medical Gas Research, 13(4), 198-201.
