Expression of miRNA-451 and miRNA-885 in Meningiomas

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dc.contributor.authorBaran, Ozgur
dc.contributor.authorKaraoglu, Adil Can
dc.contributor.authorKara, Erdogan
dc.contributor.authorBudun, Orhan
dc.contributor.authorKatar, Salim
dc.contributor.authorYilmaz, Seda Gulec
dc.contributor.authorAkdeniz, Fatma Tuba
dc.date.accessioned2024-04-24T17:18:36Z
dc.date.available2024-04-24T17:18:36Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground/Aim: Meningiomas are one of the most common intracranial tumors, accounting for 30% of the tumors of the central nervous system. MicroRNAs (miRNAs) are noncoding RNAs containing approximately 18-22 nucleotides that regulate gene expression by interfering with transcription or inhibiting translation. Recent studies have reported that miRNAs could provide information about the molecular pathogenesis of several types of tumors. This study aimed to examine the expression levels of miRNA-885 and -451 and to determine their potential roles as biomarkers in meningioma. Materials and Methods: In total, 29 patients with meningioma (9 males and 20 females) were included in this study. The expression levels of miRNA were determined using real-time polymerase chain reaction. In addition, receiver operating characteristic curve analysis was used to analyze the predictive potential of miRNAs. Results: Our results indicated a significant increase in miRNA-451 expression levels (p=0.003); however, there was no significant change in miRNA-885 expression levelsen_US
dc.identifier.doi10.21873/invivo.13354
dc.identifier.endpage2479en_US
dc.identifier.issn0258-851X
dc.identifier.issn1791-7549
dc.identifier.issue6en_US
dc.identifier.pmid37905647
dc.identifier.scopus2-s2.0-85175878343
dc.identifier.scopusqualityQ2
dc.identifier.startpage2473en_US
dc.identifier.urihttps://doi.org/10.21873/invivo.13354
dc.identifier.urihttps://hdl.handle.net/11468/18844
dc.identifier.volume37en_US
dc.identifier.wosWOS:001112634900051
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInt Inst Anticancer Researchen_US
dc.relation.ispartofIn Vivo
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMeningiomasen_US
dc.subjectMicrorna-451en_US
dc.subjectMicrorna-885en_US
dc.subjectGene Expressionen_US
dc.subjectNeuro-Oncologyen_US
dc.titleExpression of miRNA-451 and miRNA-885 in Meningiomasen_US
dc.titleExpression of miRNA-451 and miRNA-885 in Meningiomas
dc.typeArticleen_US

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