Paraoxonase and arylesterase activities in fibromyalgia

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dc.contributor.authorAltindag, Ozlem
dc.contributor.authorGur, Ali
dc.contributor.authorCalgan, Nazife
dc.contributor.authorSoran, Neslihan
dc.contributor.authorCelik, Hakim
dc.contributor.authorSelek, Sahabettin
dc.date.accessioned2024-04-24T17:14:48Z
dc.date.available2024-04-24T17:14:48Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractPublished by Maney Publishing ( c) W. S. Maney & Son Limited We aimed to evaluate the association of serum paraoxonase and arylesterase activities and oxidative/ antioxidative status in patients with fibromyalgia. Forty-two patients with fibromyalgia and 53 healthy controls were included in the study. Serum paraoxonase and arylesterase activities were measured spectrophotometrically. Oxidative and antioxidative status were evaluated by measuring serum lipid hydroperoxide ( LOOH) levels, total antioxidant status ( TAS) and free sulfhydryl groups ( - SH = total thiol). Lipid parameters were determined by routine laboratory methods. Serum paraoxonase and arylesterase activities, and TAS were lower in patients with fibromyalgia than in controls ( P < 0.001, for all), and the - SH level was also lower in the patient group ( P = 0.03). LOOH levels were higher in the patient group than in controls ( P = 0.01). Our results suggest that patients with fibromyalgia were exposed to oxidative stress, and paraoxonase and arylesterase activities were decreased in these patients. Patients with fibromyalgia might be prone to development of atherosclerosis with reduced paraoxonase and arylesterase activities.en_US
dc.identifier.doi10.1179/rer.2007.12.3.134
dc.identifier.endpage138en_US
dc.identifier.issn1351-0002
dc.identifier.issn1743-2928
dc.identifier.issue3en_US
dc.identifier.pmid17623520
dc.identifier.scopus2-s2.0-34547117603
dc.identifier.scopusqualityQ2
dc.identifier.startpage134en_US
dc.identifier.urihttps://doi.org/10.1179/rer.2007.12.3.134
dc.identifier.urihttps://hdl.handle.net/11468/18197
dc.identifier.volume12en_US
dc.identifier.wosWOS:000249321000004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRedox Report
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFibromyalgiaen_US
dc.subjectParaoxonaseen_US
dc.subjectArylesteraseen_US
dc.subjectOxidative Stressen_US
dc.titleParaoxonase and arylesterase activities in fibromyalgiaen_US
dc.titleParaoxonase and arylesterase activities in fibromyalgia
dc.typeArticleen_US

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