Periprosthetic infection risks and predictive value of HbA1c/albumin ratio for total joint arthroplasty in patients with diabetes mellitus

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dc.authorid0000-0002-7290-6798en_US
dc.authorid0000-0002-2999-2141en_US
dc.contributor.authorYiğit, Şeyhmus
dc.contributor.authorAkar, Mehmet Sait
dc.date.accessioned2023-10-25T08:17:14Z
dc.date.available2023-10-25T08:17:14Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Ortopedi ve Travmatoloji Ana Bilim Dalıen_US
dc.description.abstractOBJECTIVE: There are no gold standard markers to estimate the risk of developing periprosthetic infections in diabetes mellitus. Our aim is to compare the risks of periprosthetic infection in patients undergoing total joint arthroplasty with diabetes mellitus and to investigate the predictive significance of the HbA1c/ albumin ratio. PATIENTS AND METHODS: Between January 2012 and January 2020, 690 patients who underwent total joint arthroplasty were analysed. 264 diabetic patients were included in the study. 104 of them had periprosthetic infection. 8 risk factors (Hba1c/albumin, HbA1c, albumin, age, BMI, ASA, hospital stay, operation time) were analysed. RESULTS: The rate of HbA1c/albumin was 14.6 times higher than the patients with ≤2.37 cut-off value. (Hba1c/albumin ratio (odds ratio (OR) = 14.6, 95% CI: 3.18-67.1, p: 0.01). HbA1c (OR = 2.6, 95% CI: 1.529-4.754, p: 0.001), BMI (OR = 1.6, 95% CI: 1.168-2.199, p<0.003), DM (OR = 0.365, 95% CI: 0.135-0.987, p: 0.04) and glucose (OR = 1.016, 95% CI: 1.004-1.029, p: 0.011) were risk factures for periprosthetic infection. Albumin (OR = 0.503, 95% CI: 0.109-2.314, p: 0.378) did not pose a significant risk for periprosthetic infection. CONCLUSIONS: According to our findings, the HbA1c/albumin ratio has a more prognostic capacity than other risks in determining the risk of periprosthetic infection for total joint arthroplasty. HbA1c/albumin ratio is a cheap and easyto-apply marker. Patients with an HbA1c/albumin cut-off ratio above 2.37 mg/dl in total joint arthroplasty should be followed more closely for the risk of periprosthetic infection.en_US
dc.identifier.citationYiğit, Ş. ve Akar, M. S. (2023). Periprosthetic infection risks and predictive value of HbA1c/albumin ratio for total joint arthroplasty in patients with diabetes mellitus. European Review for Medical and Pharmacological Sciences, 27(5), 1869-1874.en_US
dc.identifier.doi10.26355/eurrev_202303_31551
dc.identifier.endpage1874en_US
dc.identifier.issn1128-3602
dc.identifier.issue5en_US
dc.identifier.pmid36930483
dc.identifier.scopus2-s2.0-85150666717
dc.identifier.scopusqualityQ2
dc.identifier.startpage1869en_US
dc.identifier.urihttps://www.europeanreview.org/wp/wp-content/uploads/1869-1874-1.pdf
dc.identifier.urihttps://hdl.handle.net/11468/12930
dc.identifier.volume27en_US
dc.identifier.wosWOS:000959553700021
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYiğit, Şeyhmus
dc.institutionauthorAkar, Mehmet Sait
dc.language.isoenen_US
dc.publisherVerduci Editore s.r.len_US
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHbA1c/albumin ratioen_US
dc.subjectPeriprosthetic infectionen_US
dc.subjectRisk factorsen_US
dc.subjectTotal joint arthroplastyen_US
dc.subjectDiabetes mellitusen_US
dc.titlePeriprosthetic infection risks and predictive value of HbA1c/albumin ratio for total joint arthroplasty in patients with diabetes mellitusen_US
dc.titlePeriprosthetic infection risks and predictive value of HbA1c/albumin ratio for total joint arthroplasty in patients with diabetes mellitus
dc.typeArticleen_US

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