Periprosthetic infection risks and predictive value of HbA1c/albumin ratio for total joint arthroplasty in patients with diabetes mellitus
Yükleniyor...
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Verduci Editore s.r.l
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVE: There are no gold
standard markers to estimate the risk of developing periprosthetic infections in diabetes mellitus. Our aim is to compare the risks of periprosthetic infection in patients undergoing total joint
arthroplasty with diabetes mellitus and to investigate the predictive significance of the HbA1c/
albumin ratio.
PATIENTS AND METHODS: Between January 2012 and January 2020, 690 patients who underwent total joint arthroplasty were analysed.
264 diabetic patients were included in the study.
104 of them had periprosthetic infection. 8 risk
factors (Hba1c/albumin, HbA1c, albumin, age,
BMI, ASA, hospital stay, operation time) were
analysed.
RESULTS: The rate of HbA1c/albumin was 14.6
times higher than the patients with ≤2.37 cut-off
value. (Hba1c/albumin ratio (odds ratio (OR) =
14.6, 95% CI: 3.18-67.1, p: 0.01). HbA1c (OR = 2.6,
95% CI: 1.529-4.754, p: 0.001), BMI (OR = 1.6, 95%
CI: 1.168-2.199, p<0.003), DM (OR = 0.365, 95%
CI: 0.135-0.987, p: 0.04) and glucose (OR = 1.016,
95% CI: 1.004-1.029, p: 0.011) were risk factures
for periprosthetic infection. Albumin (OR = 0.503,
95% CI: 0.109-2.314, p: 0.378) did not pose a significant risk for periprosthetic infection.
CONCLUSIONS: According to our findings,
the HbA1c/albumin ratio has a more prognostic
capacity than other risks in determining the risk
of periprosthetic infection for total joint arthroplasty. HbA1c/albumin ratio is a cheap and easyto-apply marker. Patients with an HbA1c/albumin
cut-off ratio above 2.37 mg/dl in total joint arthroplasty should be followed more closely for
the risk of periprosthetic infection.
Açıklama
Anahtar Kelimeler
HbA1c/albumin ratio, Periprosthetic infection, Risk factors, Total joint arthroplasty, Diabetes mellitus
Kaynak
European Review for Medical and Pharmacological Sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
27
Sayı
5
Künye
Yiğit, Ş. ve Akar, M. S. (2023). Periprosthetic infection risks and predictive value of HbA1c/albumin ratio for total joint arthroplasty in patients with diabetes mellitus. European Review for Medical and Pharmacological Sciences, 27(5), 1869-1874.
