Serum leptin level in women with unexplained infertility

Basit Öğe Kaydı
dc.contributor.authorDemir, Bulent
dc.contributor.authorGuven, Suleyman
dc.contributor.authorGuven, Emie Seda Guvendag
dc.contributor.authorAtamer, Yildiz
dc.contributor.authorGunalp, G. Serdar
dc.contributor.authorGul, Talip
dc.date.accessioned2024-04-24T16:15:22Z
dc.date.available2024-04-24T16:15:22Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: The aim of this study was to compare serum levels of leptin in women with unexplained infertility with fertile subjects. Material and method: Serum leptin levels of 27 infertile and 30 fertile women on day 3 of the menstrual cycle were assessed and compared in this prospective age and body mass index (BMI) comparable controlled study. Results: The mean age in the infertile group was 29.3 (range, 23-38), while this figure was 28.9 (range, 19-39) in the fertile group; the mean BMIs were 24.5 (range, 20.6-27.8) and 25.0 (range, 21.8-28.7), respectively. The mean serum leptin level was significantly higher in women with unexplained infertility compared with fertile subjects. Considering normal weight subjects, mean serum leptin levels were increased significantly in the unexplained infertile group compared with the fertile group (7.2 (range, 4.3-10.4) versus 3.5 (range, 1.9-6.2) ng/ml, respectively;p < 0.0001, Mann-Whitney U-test). The significant increase in serum leptin levels was observed also in overweight patients (6.8 (range, 1.3-5.2) versus 3.3 (range, 4.2-8.9) ng/ml, respectively; p < 0.0001, Mann-Whitney U-test). Conclusion: A significant difference in serum leptin levels between unexplained infertile and fertile women suggests that this cytokine may be involved in pathophysiology of unexplained infertility. (c) 2007 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.jri.2007.04.001
dc.identifier.endpage149en_US
dc.identifier.issn0165-0378
dc.identifier.issue2en_US
dc.identifier.pmid17485120
dc.identifier.scopus2-s2.0-34548536663
dc.identifier.scopusqualityQ1
dc.identifier.startpage145en_US
dc.identifier.urihttps://doi.org/10.1016/j.jri.2007.04.001
dc.identifier.urihttps://hdl.handle.net/11468/15774
dc.identifier.volume75en_US
dc.identifier.wosWOS:000250278100010
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofJournal of Reproductive Immunology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLeptinen_US
dc.subjectPathophysiologyen_US
dc.subjectSerum Levelen_US
dc.subjectUnexplained Infertilityen_US
dc.titleSerum leptin level in women with unexplained infertilityen_US
dc.titleSerum leptin level in women with unexplained infertility
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu