Relation between severity of injury and the early activation of interleukins in multiple-injured patients

Basit Öğe Kaydı
dc.contributor.authorYagmur, Y
dc.contributor.authorOzturk, H
dc.contributor.authorUnaldi, M
dc.contributor.authorGedik, E
dc.date.accessioned2024-04-24T17:14:27Z
dc.date.available2024-04-24T17:14:27Z
dc.date.issued2005
dc.departmentDicle Üniversitesien_US
dc.description40th Congress of the European-Society-for-Surgical-Research -- MAY 25-28, 2005 -- Konya, TURKEYen_US
dc.description.abstractThe aim of this study was to evaluate the relation between severity of injury and the early activation of interleukins in multiple-injured patients. Ninety-nine patients with multiple injuries were included in this prospective study. Plasma levels of interleukin (IL)-1, IL-2, IL-6, IL-8 and TNF-alpha were measured. Injury Severity Score ( ISS), Revised Trauma Score (RTS), Glasgow Coma Score (GCS) and the Acute Physiology and Chronic Health Evaluation II (APACHE- II) were all recorded. Of the 99 patients, 82 were male and 17 were female. The mean age was 26.6 +/- 20.7 years. The mortality rate for this series was 17%. Patients who died from trauma exhibited a significant increase for IL-2, IL-6 and IL-8 in comparison with patients who survived. Significant differences for ISS, RTS and GCS were found between survivors and non-survivors. Values in all patients with ISS 1 16 were increased and these increases were significant for IL-6 and IL-2. These data show that the initial increase of IL-2, IL-6 and IL-8 might predict the patients with a high possibility of mortality and a significant increase of IL-2 and IL-6 in patients with ISS > 16 might be used in a new developed trauma score combined with ISS as an indicator for the injury severity. Copyright (C) 2005 S. Karger AG, Basel.en_US
dc.description.sponsorshipEuropean Soc Surg Resen_US
dc.identifier.doi10.1159/000090337
dc.identifier.endpage364en_US
dc.identifier.issn0014-312X
dc.identifier.issn1421-9921
dc.identifier.issue6en_US
dc.identifier.pmid16465061
dc.identifier.scopus2-s2.0-32244435241
dc.identifier.scopusqualityQ2
dc.identifier.startpage360en_US
dc.identifier.urihttps://doi.org/10.1159/000090337
dc.identifier.urihttps://hdl.handle.net/11468/17944
dc.identifier.volume37en_US
dc.identifier.wosWOS:000235209400008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofEuropean Surgical Research
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultiple-Injured Patientsen_US
dc.subjectCytokinesen_US
dc.subjectMortalityen_US
dc.titleRelation between severity of injury and the early activation of interleukins in multiple-injured patientsen_US
dc.titleRelation between severity of injury and the early activation of interleukins in multiple-injured patients
dc.typeConference Objecten_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu