Phytochemical contents of different parts of the seeded raisins from the South-East Anatolia: Enzyme inhibitory potential of pulp extracts

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dc.authorid0000-0003-3194-5165en_US
dc.authorid0000-0002-0988-9462en_US
dc.authorid0000-0002-2861-5504en_US
dc.authorid0000-0001-6571-6032en_US
dc.authorid0000-0002-6202-1515en_US
dc.authorid0000-0002-4090-7227en_US
dc.authorid0000-0002-2193-8386en_US
dc.contributor.authorKarataş, Dilek Değirmenci
dc.contributor.authorÖz, Veysi
dc.contributor.authorYener, İsmail
dc.contributor.authorAkdeniz, Mehmet
dc.contributor.authorErek, Figen
dc.contributor.authorAydın, Işıl
dc.contributor.authorYiğitkan, Serkan
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorErtaş, Abdulselam
dc.date.accessioned2023-03-09T06:33:02Z
dc.date.available2023-03-09T06:33:02Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Ziraat Fakültesi, Bahçe Bitkileri Bölümüen_US
dc.description.abstractIn this study, some phytochemical properties of six seeded raisin species that are mainly cultivated in Southeastern Anatolia were investigated. Additionally, some physical and quality characteristics, phenolic contents (by LC-MS/MS; Liquid Chromatography Tandem Mass/Mass Spectrometer System), anticholinesterase, and antioxidant capacities (DPPH; 2,2-diphenyl-1-picrylhydrazyl free-radical scavenging, ABTS; 2,2-azinobis(3-ethylbenzothiazoline-6-sulphonic acid cation-radical scavenging activity and CUPRAC; cupric reducing antioxidant capacity) of the cultivars were investigated on ground raisins. In all three methods, the antioxidant activity values of seed extracts were determined to be higher than those of leaf and pulp extracts. Remarkably, the seed extract of Banazi Siyahi showed the highest antioxidant activity in ABTS (IC50: 4.35 +/- 0.02 mu g/mL), DPPH (IC50: 10.78 +/- 0.78 mu g/mL), and CUPRAC (A0.5: 9.33 +/- 0.45 mu g/mL) methods. Additionally, the ethanol extracts of all pulp samples showed higher anticholinesterase activity against acetyl-(AChE) and butyrylcholinesterase (BChE) enzymes than galantamine. According to the LC-MS/MS results, catechin (21.362 mg analyte/g extract) and epicatechin (44.667 mg analyte/g extract) found to be quite rich in Kerkus seed extract and isoquercitrin (116.873 mg analyte/g extract) and astragalin (31.915 mg analyte/g extract) detected to be quite rich in Banazi Siyahi leaf extract. Considering the mineral content of the varieties and the soil samples they grow in, all of the grape varieties analyzed in the study was found to be rich. Based on these findings, it might be suggested that Banazi Siyahi and Kerkus varieties have potential to be utilized in pharmaceutical and food industries, due to their contents of catechins, isoquercitrin and astragalin.en_US
dc.identifier.citationKarataş, D.D., Öz, V., Yener, İ., Akdeniz, M., Erek, F., Aydın, I. ve diğerleri. (2022). Phytochemical contents of different parts of the seeded raisins from the South-East Anatolia: Enzyme inhibitory potential of pulp extracts. Chemistry & Biodiversity, 19(3), 1-11.en_US
dc.identifier.doi10.1002/cbdv.202100844
dc.identifier.endpage11en_US
dc.identifier.issn1612-1872
dc.identifier.issn1612-1880
dc.identifier.issue3en_US
dc.identifier.pmid35001497
dc.identifier.scopus2-s2.0-85123759437
dc.identifier.scopusqualityQ3
dc.identifier.startpage1en_US
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1002/cbdv.202100844
dc.identifier.urihttps://hdl.handle.net/11468/11334
dc.identifier.volume19en_US
dc.identifier.wosWOS:000748347800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKarataş, Dilek Değirmenci
dc.institutionauthorÖz, Veysi
dc.institutionauthorYener, İsmail
dc.institutionauthorErek, Figen
dc.institutionauthorAydın, Işıl
dc.institutionauthorYiğitkan, Serkan
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.institutionauthorErtaş, Abdulselam
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag GMBHen_US
dc.relation.ispartofChemistry & Biodiversity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVitis viniferaen_US
dc.subjectAntioxidanten_US
dc.subjectAnticholinesteraseen_US
dc.subjectLC-MSen_US
dc.subjectMSen_US
dc.subjectCatechinsen_US
dc.subjectIsoquercitrinen_US
dc.subjectMineral contenten_US
dc.titlePhytochemical contents of different parts of the seeded raisins from the South-East Anatolia: Enzyme inhibitory potential of pulp extractsen_US
dc.titlePhytochemical contents of different parts of the seeded raisins from the South-East Anatolia: Enzyme inhibitory potential of pulp extracts
dc.typeArticleen_US

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