Evaluation of the Relationship between Brain-Derived Neurotropic Factor Levels and the Stroop Interference Effect in Children with Attention-Deficit Hyperactivity Disorder

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dc.contributor.authorSimsek, Seref
dc.contributor.authorGencoglan, Salih
dc.contributor.authorYuksel, Tugba
dc.contributor.authorKaplan, Ibrahim
dc.contributor.authorAktas, Huseyin
dc.contributor.authorAlaca, Rumeysa
dc.date.accessioned2024-04-24T17:27:29Z
dc.date.available2024-04-24T17:27:29Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: Brain-derived neurotropic factor (BDNF) has been suggested to play a role in the pathogenesis of attention-deficit hyperactivity disorder (ADHD). In addition, impairment in executive functions has been reported in children with ADHD. This study investigated the presence of a relationship between Stroop test scores and BDNF levels in children with ADHD. Methods: The study was conducted in the Department of Child Psychiatry at Dicle University. The study included 49 children between 6 and 15 years of age (M/F: 42/7), who were diagnosed with ADHD according to DSM-IV, and who did not receive previous therapy. Similar in terms of age and gender to the ADHD group, 40 children were selected in the control group. The Kiddie Schedule for Affective Disorders and Schizophrenia, Present and Lifetime version was administered to all participants. Parents and teachers were administered Turgay DSM-IV-based Child and Adolescent Behavior Disorders Screening and Rating Scale to measure symptom severity in children with ADHD. Children with ADHD underwent the Stroop test. BDNF levels were evaluated in serum by ELISA. Results: The ADHD and control groups did not differ in terms of BDNF levels. BDNF levels did not differ between ADHD subtypes. There was also no relationship between the Stroop test interference scores and BDNF levels. Conclusion: The findings of the present study are in line with those in studies that demonstrated no significant role of BDNF in the pathogenesis of ADHD.en_US
dc.identifier.doi10.5152/npa.2016.10234
dc.identifier.endpage352en_US
dc.identifier.issn1300-0667
dc.identifier.issn1309-4866
dc.identifier.issue4en_US
dc.identifier.pmid28360811
dc.identifier.scopus2-s2.0-85006488652
dc.identifier.scopusqualityQ3
dc.identifier.startpage348en_US
dc.identifier.trdizinid262689
dc.identifier.urihttps://doi.org/10.5152/npa.2016.10234
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/262689
dc.identifier.urihttps://hdl.handle.net/11468/19990
dc.identifier.volume53en_US
dc.identifier.wosWOS:000391572500012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofNoropsikiyatri Arsivi-Archives of Neuropsychiatry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAttention-Deficit Hyperactivity Disorderen_US
dc.subjectBrain-Derived Neurotropic Factoren_US
dc.subjectStroopen_US
dc.subjectPathophysiologyen_US
dc.subjectExecutive Functionsen_US
dc.titleEvaluation of the Relationship between Brain-Derived Neurotropic Factor Levels and the Stroop Interference Effect in Children with Attention-Deficit Hyperactivity Disorderen_US
dc.titleEvaluation of the Relationship between Brain-Derived Neurotropic Factor Levels and the Stroop Interference Effect in Children with Attention-Deficit Hyperactivity Disorder
dc.typeArticleen_US

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