Assessment of perioperative antimicrobial prophylaxis using ATC/DDD methodology

dc.authorid0000-0003-4577-4475en_US
dc.authorid0000-0002-1173-5286en_US
dc.contributor.authorBozkurt, Fatma
dc.contributor.authorKaya, Şafak
dc.contributor.authorGülsün, Serda
dc.contributor.authorTekin, Recep
dc.contributor.authorDeveci, Özcan
dc.contributor.authorDayan, Saim
dc.contributor.authorHoşo?lu, Salih
dc.date.accessioned2024-01-18T06:14:21Z
dc.date.available2024-01-18T06:14:21Z
dc.date.issued2013en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalıen_US
dc.description.abstractObjectives: In the light of international experience and guidelines and in order to improve the quality of perioperative antimicrobial prophylaxis (PAP), various hospitals have set up their own multidisciplinary healthcare teams and have evaluated the density of PAP through close supervision and interventions. The aim of the present study was to compare the density, quality, and cost of PAP before and after an intervention implemented at our hospital in order to increase the quality of PAP. Methods: PAP was monitored using a form prepared in line with the international guidelines, which was completed by the infection control nurse under the supervision of the infectious diseases specialist. In order to reduce the frequent errors in our PAP procedures, an intervention was implemented, and the period before this intervention (January–April 2011) was compared with the post-intervention period 1 year later (January–April 2012). The density of PAP was calculated according to the Anatomical Therapeutic Chemical classification/defined daily dose (ATC/DDD) methodology. Results: A total of 2398 patients received PAP during this period. The most frequently used antibiotic before and after the intervention was cefazolin. Its use further increased after the intervention (p < 0.001). After the intervention, the ratio of the correct timing of the first antibiotic dose increased from 91.7% to 99.0% (p < 0.001), while the excessively long administration of PAP was reduced from 77.0% to 44.7% (p < 0.001). The ratio of full compliance with the guidelines increased from 15.5% to 40.2% (p < 0.001) and the rate of surgical site infections dropped from 18.5% to 12.0%. The density of antibiotic use dropped from 305.7 DDD/100 procedures = 3.1 DDD/procedure to 162.1 DDD/100 procedures = 1.6 DDD/procedure. Conclusion: The quality of PAP may be improved through better compliance with healthcare guidelines, close supervision, and training activities. Also, surgical site infections and the cost of PAP may be reduced through more appropriate antibiotic use, thus contributing to the national healthcare budget.en_US
dc.identifier.citationBozkurt, F., Kaya, Ş., Gülsün, S., Tekin, R., Deveci, Ö., Dayan, S. ve diğerleri. (2013). Assessment of perioperative antimicrobial prophylaxis using ATC/DDD methodology. International Journal of Infectious Diseases, 17(2), e1212-e1217.en_US
dc.identifier.doi10.1016/j.ijid.2013.08.003
dc.identifier.endpagee1217en_US
dc.identifier.issn1878-3511
dc.identifier.issue2en_US
dc.identifier.pmid24120217
dc.identifier.scopus2-s2.0-84888428297
dc.identifier.scopusqualityQ1
dc.identifier.startpagee1212en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1201971213002634?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/13221
dc.identifier.volume17en_US
dc.identifier.wosWOS:000327546800022
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBozkurt, Fatma
dc.institutionauthorKaya, Şafak
dc.institutionauthorGülsün, Serda
dc.institutionauthorTekin, Recep
dc.institutionauthorDeveci, Özcan
dc.institutionauthorDayan, Saim
dc.institutionauthorHoşoǧlu, Salih
dc.language.isoenen_US
dc.publisherElsevier Ltd.en_US
dc.relation.ispartofInternational Journal of Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectATC/DDD indexen_US
dc.subjectCompatibilityen_US
dc.subjectCosten_US
dc.subjectPerioperative antimicrobial prophylaxisen_US
dc.subjectSuperintendenceen_US
dc.subjectTurkeyen_US
dc.titleAssessment of perioperative antimicrobial prophylaxis using ATC/DDD methodologyen_US
dc.titleAssessment of perioperative antimicrobial prophylaxis using ATC/DDD methodology
dc.typeArticleen_US

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