Assessment of perioperative antimicrobial prophylaxis using ATC/DDD methodology
Yükleniyor...
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ltd.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: In the light of international experience and guidelines and in order to improve the quality of
perioperative antimicrobial prophylaxis (PAP), various hospitals have set up their own multidisciplinary
healthcare teams and have evaluated the density of PAP through close supervision and interventions.
The aim of the present study was to compare the density, quality, and cost of PAP before and after an
intervention implemented at our hospital in order to increase the quality of PAP.
Methods: PAP was monitored using a form prepared in line with the international guidelines, which was
completed by the infection control nurse under the supervision of the infectious diseases specialist. In
order to reduce the frequent errors in our PAP procedures, an intervention was implemented, and the
period before this intervention (January–April 2011) was compared with the post-intervention period 1
year later (January–April 2012). The density of PAP was calculated according to the Anatomical
Therapeutic Chemical classification/defined daily dose (ATC/DDD) methodology.
Results: A total of 2398 patients received PAP during this period. The most frequently used antibiotic
before and after the intervention was cefazolin. Its use further increased after the intervention
(p < 0.001). After the intervention, the ratio of the correct timing of the first antibiotic dose increased
from 91.7% to 99.0% (p < 0.001), while the excessively long administration of PAP was reduced from
77.0% to 44.7% (p < 0.001). The ratio of full compliance with the guidelines increased from 15.5% to 40.2%
(p < 0.001) and the rate of surgical site infections dropped from 18.5% to 12.0%. The density of antibiotic
use dropped from 305.7 DDD/100 procedures = 3.1 DDD/procedure to 162.1 DDD/100 procedures = 1.6
DDD/procedure.
Conclusion: The quality of PAP may be improved through better compliance with healthcare guidelines,
close supervision, and training activities. Also, surgical site infections and the cost of PAP may be reduced
through more appropriate antibiotic use, thus contributing to the national healthcare budget.
Açıklama
Anahtar Kelimeler
ATC/DDD index, Compatibility, Cost, Perioperative antimicrobial prophylaxis, Superintendence, Turkey
Kaynak
International Journal of Infectious Diseases
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
17
Sayı
2
Künye
Bozkurt, F., Kaya, Ş., Gülsün, S., Tekin, R., Deveci, Ö., Dayan, S. ve diğerleri. (2013). Assessment of perioperative antimicrobial prophylaxis using ATC/DDD methodology. International Journal of Infectious Diseases, 17(2), e1212-e1217.
