New inflammatory predictors for non-valvular atrial fibrillation: echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio

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dc.contributor.authorAcet, Halit
dc.contributor.authorErtas, Faruk
dc.contributor.authorAkil, Mehmet Ata
dc.contributor.authorOylumlu, Mustafa
dc.contributor.authorPolat, Nihat
dc.contributor.authorYildiz, Abdulkadir
dc.contributor.authorBilik, Mehmet Zihni
dc.date.accessioned2024-04-24T16:02:06Z
dc.date.available2024-04-24T16:02:06Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe objective of this study was to investigate the relationship of echocardiographic epicardial fat thickness (EFT) and neutrophil to lymphocyte ratio (NLR) with different types of non-valvular atrial fibrillation (AF) in a clinical setting. A total of 197 consecutive patients were enrolled in the study. Seventy-one patients had paroxysmal non-valvular AF, 63 patients had persistent/permanent non-valvular AF, and 63 patients had sinus rhythm (control group). EFT was measured with echocardiography, while NLR was measured by dividing neutrophil count by lymphocyte count. EFT was significantly higher in patients with paroxysmal non-valvular AF compared with those in the sinus rhythm group (6.6 +/- A 0.7 vs. 5.0 +/- A 0.9 mm, p < 0.001). Persistent/permanent non-valvular AF patients had a significantly larger EFT compared with those with paroxysmal AF (8.3 +/- A 1.1 vs. 6.6 +/- A 0.7 mm, p < 0.001). EFT had a significant relationship with paroxysmal non-valvular AF (odds ratio 4.672, 95 % CI 2.329-9.371, p < 0.001) and persistent/permanent non-valvular AF (OR 24.276, 95 % CI 9.285-63.474, p < 0.001). NLR was significantly higher in those with paroxysmal non-valvular AF compared with those in the sinus rhythm group (2.5 +/- A 0.6 vs. 1.8 +/- A 0.4, p < 0.001). Persistent/permanent non-valvular AF patients had a significantly larger NLR when compared with paroxysmal non-valvular AF patients (3.4 +/- A 0.6, vs. 2.5 +/- A 0.6, p < 0.001). NLR (> 2.1) had a significant relationship with non-valvular AF (OR 11.313, 95 % CI 3.025-42.306, b 2.426, p < 0.001). EFT and NLR are highly associated with types of non-valvular AF independent of traditional risk factors. EFT measured by echocardiography and NLR appears to be related to the duration and severity of AF.en_US
dc.identifier.doi10.1007/s10554-013-0317-4
dc.identifier.endpage89en_US
dc.identifier.issn1569-5794
dc.identifier.issn1573-0743
dc.identifier.issue1en_US
dc.identifier.pmid24162180en_US
dc.identifier.scopus2-s2.0-84899090472en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage81en_US
dc.identifier.urihttps://doi.org/10.1007/s10554-013-0317-4
dc.identifier.urihttps://hdl.handle.net/11468/14633
dc.identifier.volume30en_US
dc.identifier.wosWOS:000330342800009
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Journal of Cardiovascular Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpicardial Fat Thicknessen_US
dc.subjectEchocardiographyen_US
dc.subjectNeutrophil To Lymphocyte Ratioen_US
dc.subjectNon-Valvular Atrial Fibrillationen_US
dc.subjectLeft Atrial Enlargementen_US
dc.titleNew inflammatory predictors for non-valvular atrial fibrillation: echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratioen_US
dc.typeArticleen_US

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