New inflammatory predictors for non-valvular atrial fibrillation: echocardiographic epicardial fat thickness and neutrophil to lymphocyte ratio
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Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The objective of this study was to investigate the relationship of echocardiographic epicardial fat thickness (EFT) and neutrophil to lymphocyte ratio (NLR) with different types of non-valvular atrial fibrillation (AF) in a clinical setting. A total of 197 consecutive patients were enrolled in the study. Seventy-one patients had paroxysmal non-valvular AF, 63 patients had persistent/permanent non-valvular AF, and 63 patients had sinus rhythm (control group). EFT was measured with echocardiography, while NLR was measured by dividing neutrophil count by lymphocyte count. EFT was significantly higher in patients with paroxysmal non-valvular AF compared with those in the sinus rhythm group (6.6 +/- A 0.7 vs. 5.0 +/- A 0.9 mm, p < 0.001). Persistent/permanent non-valvular AF patients had a significantly larger EFT compared with those with paroxysmal AF (8.3 +/- A 1.1 vs. 6.6 +/- A 0.7 mm, p < 0.001). EFT had a significant relationship with paroxysmal non-valvular AF (odds ratio 4.672, 95 % CI 2.329-9.371, p < 0.001) and persistent/permanent non-valvular AF (OR 24.276, 95 % CI 9.285-63.474, p < 0.001). NLR was significantly higher in those with paroxysmal non-valvular AF compared with those in the sinus rhythm group (2.5 +/- A 0.6 vs. 1.8 +/- A 0.4, p < 0.001). Persistent/permanent non-valvular AF patients had a significantly larger NLR when compared with paroxysmal non-valvular AF patients (3.4 +/- A 0.6, vs. 2.5 +/- A 0.6, p < 0.001). NLR (> 2.1) had a significant relationship with non-valvular AF (OR 11.313, 95 % CI 3.025-42.306, b 2.426, p < 0.001). EFT and NLR are highly associated with types of non-valvular AF independent of traditional risk factors. EFT measured by echocardiography and NLR appears to be related to the duration and severity of AF.
Açıklama
Anahtar Kelimeler
Epicardial Fat Thickness, Echocardiography, Neutrophil To Lymphocyte Ratio, Non-Valvular Atrial Fibrillation, Left Atrial Enlargement
Kaynak
International Journal of Cardiovascular Imaging
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
30
Sayı
1
