Neonatal tetanus: A continuing challenge in the southeast of Turkey

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dc.authorid0000-0002-5299-9480en_US
dc.authorid0000-0002-8390-5109en_US
dc.contributor.authorGürkan, Fuat
dc.contributor.authorBoşnak, Mehmet
dc.contributor.authorDikici, Bünyamin
dc.contributor.authorBoşnak, Vuslat
dc.contributor.authorTaş, M. Ali
dc.contributor.authorHaspolat, Yusuf Kenan
dc.contributor.authorKara, İsmail Hamdi
dc.contributor.authorÖzkan, İlker
dc.date.accessioned2021-12-08T11:37:30Z
dc.date.available2021-12-08T11:37:30Z
dc.date.issued1999en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractNeonatal tetanus (NT) still causes signi®- cant mortality in developing countries, although in 1989 WHO adopted the goal of eliminating the disease by 1995±2000. To characterize the regional characteristics, clinical charts of 55 neonates (42 males and 13 females) admitted to the Pediatric Infectious Diseases Ward of Dicle University Hospital, Diyarbakir, Turkey with the diagnosis of NT from 1991 to 1997 were reviewed. Mean age at admittance was 8.9 4.3 days with a range of 3±25 days. Mean period for the appearance of ®rst symptoms was 5.8 days ranging between 1 and 21 days. Mean birth weight of the patients was 3369 560 g. All patients were from rural areas and were delivered at home by untrained traditional birth attendants with no prior antenatal healthcare services. Razor blade (55%), scissors (27%), and knife (18%) were the instruments used to cut the cord in non-hygienic conditions. No mothers had prior vaccination with tetanus toxoid during their pregnancy. Spasticity (76%), lack of sucking (71%), trismus (60%), fever (49%), omphalitis (44%), irritability (24%), risus sardonicus (22%), and opithotonus (15%) were the most common presenting signs and symptoms. Age at admission <7.5 days and symptoms of onset <4.9 days, risus sardonicus and opisthotonus were associated with fatal outcome. All patients were treated with human tetanus immunglobulin or equine tetanus antitoxin where available, antibiotic therapy by penicillin G (100.000 U/kg/day) and intravenous high dose diazepam (40 mg/kg/day). Overall mortality rate was 40% (22 cases), without any equipment for mechanical ventilation. Health education of mothers and birth attendants, promotion of hospital delivery and prenatal tetanus immunization of all pregnant women particularly in rural areas are recommended, if NT is to be prevented.en_US
dc.identifier.citationGürkan, F., Boşnak, M., Dikici, B., Boşnak, V., Taş, M. A., Haspolat, Y. K. ve diğerleri. (1999). Neonatal tetanus: A continuing challenge in the southeast of Turkey. European Journal of Epidemiology, 15(2), 171-174.en_US
dc.identifier.doi10.1023/a:1007500109522en_US
dc.identifier.endpage174en_US
dc.identifier.issn0393-2990
dc.identifier.issn1573-7284
dc.identifier.issue2en_US
dc.identifier.pmid10204647en_US
dc.identifier.scopus2-s2.0-0344061563en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage171en_US
dc.identifier.urihttps://hdl.handle.net/11468/8370
dc.identifier.volume15en_US
dc.identifier.wosWOS:000079330300010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGürkan, Fuat
dc.institutionauthorBoşnak, Mehmet
dc.institutionauthorDikici, Bünyamin
dc.institutionauthorBoşnak, Vuslat
dc.institutionauthorTaş, M. Ali
dc.institutionauthorHaspolat, Yusuf Kenan
dc.institutionauthorKara, İsmail Hamdi
dc.institutionauthorÖzkan, İlker
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal of Epidemiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeonatal tetanusen_US
dc.subjectPrognosisen_US
dc.subjectPublic healthen_US
dc.subjectRisk factorsen_US
dc.titleNeonatal tetanus: A continuing challenge in the southeast of Turkeyen_US
dc.typeArticleen_US

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