Neonatal tetanus: A continuing challenge in the southeast of Turkey
Yükleniyor...
Dosyalar
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Neonatal tetanus (NT) still causes signi®-
cant mortality in developing countries, although in
1989 WHO adopted the goal of eliminating the
disease by 1995±2000. To characterize the regional
characteristics, clinical charts of 55 neonates (42
males and 13 females) admitted to the Pediatric
Infectious Diseases Ward of Dicle University Hospital, Diyarbakir, Turkey with the diagnosis of NT
from 1991 to 1997 were reviewed. Mean age at admittance was 8.9 4.3 days with a range of 3±25
days. Mean period for the appearance of ®rst
symptoms was 5.8 days ranging between 1 and 21
days. Mean birth weight of the patients was
3369 560 g. All patients were from rural areas
and were delivered at home by untrained traditional
birth attendants with no prior antenatal healthcare
services. Razor blade (55%), scissors (27%), and
knife (18%) were the instruments used to cut the
cord in non-hygienic conditions. No mothers had
prior vaccination with tetanus toxoid during their
pregnancy. Spasticity (76%), lack of sucking (71%),
trismus (60%), fever (49%), omphalitis (44%),
irritability (24%), risus sardonicus (22%), and
opithotonus (15%) were the most common
presenting signs and symptoms. Age at admission
<7.5 days and symptoms of onset <4.9 days, risus
sardonicus and opisthotonus were associated with
fatal outcome. All patients were treated with human
tetanus immunglobulin or equine tetanus antitoxin
where available, antibiotic therapy by penicillin
G (100.000 U/kg/day) and intravenous high dose
diazepam (40 mg/kg/day). Overall mortality rate
was 40% (22 cases), without any equipment for
mechanical ventilation. Health education of mothers
and birth attendants, promotion of hospital delivery
and prenatal tetanus immunization of all pregnant
women particularly in rural areas are recommended,
if NT is to be prevented.
Açıklama
Anahtar Kelimeler
Neonatal tetanus, Prognosis, Public health, Risk factors
Kaynak
European Journal of Epidemiology
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
15
Sayı
2
Künye
Gürkan, F., Boşnak, M., Dikici, B., Boşnak, V., Taş, M. A., Haspolat, Y. K. ve diğerleri. (1999). Neonatal tetanus: A continuing challenge in the southeast of Turkey. European Journal of Epidemiology, 15(2), 171-174.
