Evaluation of Hedera species as herbal medicine raw materials

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dc.authorid0000-0002-8006-2054en_US
dc.authorid0000-0002-4090-7227en_US
dc.authorid0000-0003-0803-2886en_US
dc.authorid0000-0001-7617-1701en_US
dc.authorid0000-0002-8553-9093en_US
dc.authorid0000-0001-6323-0338en_US
dc.contributor.authorGökkaya, İçim
dc.contributor.authorYazıcı, Nurdan
dc.contributor.authorSeyhan, Gökçe
dc.contributor.authorÇakır, Oğuz
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorBarut, Burak
dc.contributor.authorRenda, Gülin
dc.date.accessioned2024-08-16T08:28:41Z
dc.date.available2024-08-16T08:28:41Z
dc.date.issued2024en_US
dc.departmentDicle Üniversitesi, Atatürk Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümüen_US
dc.description.abstractThis study aimed to evaluate the potential of Hedera colchica as an alternative to Hedera helix species for the treatment of mild inflammatory conditions of the upper respiratory tract and chronic inflammatory bronchial diseases. The H. colchica extract with the highest saponin content (C3S; 468.19 ± 16.01 mg HE/g dry weight) and the extract with the highest total phenol content (C1F; 108.60 ± 5.61 mg GAE/g dry weight). Chemical analysis and standardisation of the extract with the highest selective COX-2 inhibitory effect was performed using the LC-MS/MS technique. It was determined that the substances found in the highest ratio in the C1F extract were quinic acid (45.909 µg/g extract) and hesperidin (37.077 µg/g extract). As a result, secondary metabolites, in addition to saponins, found in Hedera species may also contribute to the extract’s effectiveness, more potent extracts can be obtained compared to the total extract-containing preparations available in the market.en_US
dc.identifier.citationGökkaya, İ., Yazıcı, N., Seyhan, G., Çakır, O., Yılamz, M. A., Barut, B. ve diğerleri. (2024). Evaluation of Hedera species as herbal medicine raw materials. Natural Product Research, 1-8.en_US
dc.identifier.endpage8en_US
dc.identifier.issn1478-6419
dc.identifier.pmid38949574
dc.identifier.scopus2-s2.0-85197608984
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/14786419.2024.2370044
dc.identifier.urihttps://hdl.handle.net/11468/28750
dc.identifier.wosWOS:001260312400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakScopus
dc.institutionauthorÇakır, Oğuz
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofNatural Product Research
dc.relation.isversionof10.1080/14786419.2024.2370044en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-inflammatoryen_US
dc.subjectHederaen_US
dc.subjectLC-MS/MSen_US
dc.subjectMedicinal producten_US
dc.subjectStandardisationen_US
dc.titleEvaluation of Hedera species as herbal medicine raw materialsen_US
dc.titleEvaluation of Hedera species as herbal medicine raw materials
dc.typeArticleen_US

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