Evaluation of Hedera species as herbal medicine raw materials
Yükleniyor...
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor and Francis Ltd.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
This study aimed to evaluate the potential of Hedera colchica as an alternative to Hedera helix species for the treatment of mild inflammatory conditions of the upper respiratory tract and chronic inflammatory bronchial diseases. The H. colchica extract with the highest saponin content (C3S; 468.19 ± 16.01 mg HE/g dry weight) and the extract with the highest total phenol content (C1F; 108.60 ± 5.61 mg GAE/g dry weight). Chemical analysis and standardisation of the extract with the highest selective COX-2 inhibitory effect was performed using the LC-MS/MS technique. It was determined that the substances found in the highest ratio in the C1F extract were quinic acid (45.909 µg/g extract) and hesperidin (37.077 µg/g extract). As a result, secondary metabolites, in addition to saponins, found in Hedera species may also contribute to the extract’s effectiveness, more potent extracts can be obtained compared to the total extract-containing preparations available in the market.
Açıklama
Anahtar Kelimeler
Anti-inflammatory, Hedera, LC-MS/MS, Medicinal product, Standardisation
Kaynak
Natural Product Research
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
Sayı
Künye
Gökkaya, İ., Yazıcı, N., Seyhan, G., Çakır, O., Yılamz, M. A., Barut, B. ve diğerleri. (2024). Evaluation of Hedera species as herbal medicine raw materials. Natural Product Research, 1-8.
