The evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomography

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dc.authorid0000-0003-4750-9798en_US
dc.contributor.authorGüler, Rıdvan
dc.contributor.authorAǧaçayak, Kamil Serkan
dc.date.accessioned2024-04-18T11:46:53Z
dc.date.available2024-04-18T11:46:53Z
dc.date.issued2024en_US
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Ağız-Diş-Çene Hastalıkları ve Cerrahisi Bölümüen_US
dc.description.abstractBackground: HT is a systemic disease that presents with persistent high blood pressure, which has become an important health problem due to its cause of serious complications and high prevalence in the community. Aim: This study aims to examine the bone mineral density (BMD) of male patients using different groups of antihypertensive drugs for long terms with dental volumetric tomography. Material and Methods: The study was carried out using the data of patients who applied to the Dicle University Faculty of Dentistry and underwent the Dental Volumetric Tomography (DVT) scan for any reason. The patients included in the study were divided into 4 groups according to their antihypertensive use; Group 1: 60 patients who never used hypertensive medication before, Group 2: 60 patients who received Calcium Channel Blocker treatment for over 5 years, Group 3: 60 patients who received Beta Blocker treatment for over 5 years, Group 4: 60 patients who received ACE inhibitor treatment for over 5 years. Radiomorphometric measurements were made on the DVT data and the DVT-Mandibular Index Inferior, DVT-Cortical Index, Hounsfield Unit-Cortical and Hounsfield Unit-Spongios values were calculated. The Kruskal-Wallis test, the Mann Whitney test with Bonferroni correction, the One-Way ANOVA and Post-Hoc Tukey test were used in the study. Results: A significant increase in DVT-CI and a significant decrease in HU-CORTIKAL, HU-SPONGIOS and DVT-MII values were observed in the patients using Calcium Channel Blocker medication. These findings pointed to osteoporosis. In addition, no statistically significant difference in the use of antihypertensive drugs in the Beta Blocker and ACE Inhibitor groups compared to the Control Group were found. Conclusions: The long term use of Calcium Channel Blocker group antihypertensive drugs should be considered as a risk factor for osteoporosis in men.en_US
dc.identifier.citationGüler, R. ve Ağaçayak, K. S. (2024). The evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomography. Journal of Clinical and Experimental Dentistry, 16(2), 172-177.en_US
dc.identifier.doi10.4317/jced.61240
dc.identifier.endpage177en_US
dc.identifier.issn1989-5488
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85185476434
dc.identifier.scopusqualityQ2
dc.identifier.startpage172en_US
dc.identifier.urihttp://www.medicinaoral.com/medoralfree01/aop/61240.pdf
dc.identifier.urihttps://hdl.handle.net/11468/13915
dc.identifier.volume16en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGüler, Rıdvan
dc.institutionauthorAğaçayak, Kamil Serkan
dc.language.isoenen_US
dc.publisherMedicina Oral S.L.en_US
dc.relation.ispartofJournal of Clinical and Experimental Dentistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntihypertensive drugen_US
dc.subjectBone mineral densityen_US
dc.subjectDental volumetric tomographyen_US
dc.subjectMandibleen_US
dc.subjectOsteoporosisen_US
dc.subjectRadiomorphometric indexen_US
dc.titleThe evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomographyen_US
dc.titleThe evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomography
dc.typeArticleen_US

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