The evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomography

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Küçük Resim

Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Medicina Oral S.L.

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Background: HT is a systemic disease that presents with persistent high blood pressure, which has become an important health problem due to its cause of serious complications and high prevalence in the community. Aim: This study aims to examine the bone mineral density (BMD) of male patients using different groups of antihypertensive drugs for long terms with dental volumetric tomography. Material and Methods: The study was carried out using the data of patients who applied to the Dicle University Faculty of Dentistry and underwent the Dental Volumetric Tomography (DVT) scan for any reason. The patients included in the study were divided into 4 groups according to their antihypertensive use; Group 1: 60 patients who never used hypertensive medication before, Group 2: 60 patients who received Calcium Channel Blocker treatment for over 5 years, Group 3: 60 patients who received Beta Blocker treatment for over 5 years, Group 4: 60 patients who received ACE inhibitor treatment for over 5 years. Radiomorphometric measurements were made on the DVT data and the DVT-Mandibular Index Inferior, DVT-Cortical Index, Hounsfield Unit-Cortical and Hounsfield Unit-Spongios values were calculated. The Kruskal-Wallis test, the Mann Whitney test with Bonferroni correction, the One-Way ANOVA and Post-Hoc Tukey test were used in the study. Results: A significant increase in DVT-CI and a significant decrease in HU-CORTIKAL, HU-SPONGIOS and DVT-MII values were observed in the patients using Calcium Channel Blocker medication. These findings pointed to osteoporosis. In addition, no statistically significant difference in the use of antihypertensive drugs in the Beta Blocker and ACE Inhibitor groups compared to the Control Group were found. Conclusions: The long term use of Calcium Channel Blocker group antihypertensive drugs should be considered as a risk factor for osteoporosis in men.

Açıklama

Anahtar Kelimeler

Antihypertensive drug, Bone mineral density, Dental volumetric tomography, Mandible, Osteoporosis, Radiomorphometric index

Kaynak

Journal of Clinical and Experimental Dentistry

WoS Q Değeri

Scopus Q Değeri

Q2

Cilt

16

Sayı

2

Künye

Güler, R. ve Ağaçayak, K. S. (2024). The evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomography. Journal of Clinical and Experimental Dentistry, 16(2), 172-177.