Expression of PECAM-1 and E-cadherin in the umblical cords of gestational diabetic mothers

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dc.contributor.authorTahaoǧlu, Ali Emre
dc.contributor.authorToğrul, Cihan
dc.contributor.authorKülahçıoğlu, Mehmet İrfan
dc.contributor.authorBademkıran, Muhammed Hanifi
dc.contributor.authorBalsak, Deniz
dc.contributor.authorMavigök, Erkan
dc.contributor.authorEkinci, Cenap
dc.contributor.authorDeveci, Engin
dc.date.accessioned2024-04-24T17:24:10Z
dc.date.available2024-04-24T17:24:10Z
dc.date.issued2015
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.description.abstractThe purpose of this study is to examine the changes in the umbilical cord in women diagnosed with gestational diabetes mellitus In this study, as a control group human placental tissues from normotensive pregnancies was collected from diabetic women at 28-35 weeks of gestation. Gestational diabetes (n= 20) and normal umbilical cord (n= 20) for a total of 40 units were received. GDM groups compared to the control group was significantly higher values was detected (p<0.01). In GDM group, light microscopy showed erosion of the endothelium and complete rupture of the umbilical vessels resulting in extravasation of blood within Wharton's jelly. it was observed that the cytoplasmic fragments and cell infiltration of the spill to the subepithelial layer of apoptotic cell PECAM-1 positive reaction showed. E-Cadherin in endothelial side surface of diabetes group showed weak expression in the nucleus and showed positive reaction in smooth muscle.en_US
dc.identifier.citationTahaoğlu, A. E., Toğrul, C., Külahçıoğlu, M. İ., Bademkıran, M. H., Balsak, D., Mavigök, E. ve diğerleri. (2015). Expression of PECAM-1 and E-cadherin in the umblical cords of gestational diabetic mothers. International Journal of Morphology, 33(4), 1277-1281.
dc.identifier.doi10.4067/S0717-95022015000400014
dc.identifier.endpage1281en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84956525172
dc.identifier.scopusqualityQ3
dc.identifier.startpage1277en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022015000400014
dc.identifier.urihttps://hdl.handle.net/11468/19488
dc.identifier.volume33en_US
dc.identifier.wosWOS:000371997400013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorEkinci, Cenap
dc.institutionauthorDeveci, Engin
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal of Morphology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGestational diabetes mellitusen_US
dc.subjectPecam-1en_US
dc.subjectUmblical corden_US
dc.subjectE-Cadherinen_US
dc.titleExpression of PECAM-1 and E-cadherin in the umblical cords of gestational diabetic mothersen_US
dc.titleExpression of PECAM-1 and E-cadherin in the umblical cords of gestational diabetic mothers
dc.typeArticleen_US

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