Expression of PECAM-1 and E-cadherin in the umblical cords of gestational diabetic mothers
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Soc Chilena Anatomia
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The purpose of this study is to examine the changes in the umbilical cord in women diagnosed with gestational diabetes mellitus In this study, as a control group human placental tissues from normotensive pregnancies was collected from diabetic women at 28-35 weeks of gestation. Gestational diabetes (n= 20) and normal umbilical cord (n= 20) for a total of 40 units were received. GDM groups compared to the control group was significantly higher values was detected (p<0.01). In GDM group, light microscopy showed erosion of the endothelium and complete rupture of the umbilical vessels resulting in extravasation of blood within Wharton's jelly. it was observed that the cytoplasmic fragments and cell infiltration of the spill to the subepithelial layer of apoptotic cell PECAM-1 positive reaction showed. E-Cadherin in endothelial side surface of diabetes group showed weak expression in the nucleus and showed positive reaction in smooth muscle.
Açıklama
Anahtar Kelimeler
Gestational diabetes mellitus, Pecam-1, Umblical cord, E-Cadherin
Kaynak
International Journal of Morphology
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
33
Sayı
4
Künye
Tahaoğlu, A. E., Toğrul, C., Külahçıoğlu, M. İ., Bademkıran, M. H., Balsak, D., Mavigök, E. ve diğerleri. (2015). Expression of PECAM-1 and E-cadherin in the umblical cords of gestational diabetic mothers. International Journal of Morphology, 33(4), 1277-1281.
