Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats
dc.contributor.author | Firat, Ugur | |
dc.contributor.author | Kaya, Savas | |
dc.contributor.author | Cim, Abdullah | |
dc.contributor.author | Buyukbayram, Huseyin | |
dc.contributor.author | Gokalp, Osman | |
dc.contributor.author | Dal, Mehmet Sinan | |
dc.contributor.author | Tamer, Mehmet Numan | |
dc.date.accessioned | 2024-04-24T17:12:07Z | |
dc.date.available | 2024-04-24T17:12:07Z | |
dc.date.issued | 2012 | |
dc.department | Dicle Üniversitesi | en_US |
dc.description.abstract | Eryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, it is presented that the majority of erythrocytes shows caspase-3 immunoreactivity in streptozocin- (STZ)-induced diabetic rats. Besides that, caspase-3 positive erythrocytes are aggregated and attached to vascular endothelium. In conclusion, these results may start a debate that eryptosis could have a role in the diabetic complications. | en_US |
dc.description.sponsorship | Dicle University Scientific Research Project Coordination Unit (DUBAP), Turkey [10-VF-155] | en_US |
dc.description.sponsorship | This project is supported by a grant from Dicle University Scientific Research Project Coordination Unit (DUBAP), Turkey (10-VF-155). All authors fully disclose that there is no financial or ethical conflict of interest. | en_US |
dc.identifier.doi | 10.1155/2012/316384 | |
dc.identifier.issn | 1687-5214 | |
dc.identifier.pmid | 22611373 | |
dc.identifier.scopus | 2-s2.0-84861017791 | |
dc.identifier.scopusquality | N/A | |
dc.identifier.uri | https://doi.org/10.1155/2012/316384 | |
dc.identifier.uri | https://hdl.handle.net/11468/17860 | |
dc.identifier.wos | WOS:000303728200001 | |
dc.identifier.wosquality | Q3 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | en_US |
dc.publisher | Hindawi Publishing Corporation | en_US |
dc.relation.ispartof | Experimental Diabetes Research | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | [No Keyword] | en_US |
dc.title | Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats | en_US |
dc.title | Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats | |
dc.type | Article | en_US |