Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats

dc.contributor.authorFirat, Ugur
dc.contributor.authorKaya, Savas
dc.contributor.authorCim, Abdullah
dc.contributor.authorBuyukbayram, Huseyin
dc.contributor.authorGokalp, Osman
dc.contributor.authorDal, Mehmet Sinan
dc.contributor.authorTamer, Mehmet Numan
dc.date.accessioned2024-04-24T17:12:07Z
dc.date.available2024-04-24T17:12:07Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractEryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, it is presented that the majority of erythrocytes shows caspase-3 immunoreactivity in streptozocin- (STZ)-induced diabetic rats. Besides that, caspase-3 positive erythrocytes are aggregated and attached to vascular endothelium. In conclusion, these results may start a debate that eryptosis could have a role in the diabetic complications.en_US
dc.description.sponsorshipDicle University Scientific Research Project Coordination Unit (DUBAP), Turkey [10-VF-155]en_US
dc.description.sponsorshipThis project is supported by a grant from Dicle University Scientific Research Project Coordination Unit (DUBAP), Turkey (10-VF-155). All authors fully disclose that there is no financial or ethical conflict of interest.en_US
dc.identifier.doi10.1155/2012/316384
dc.identifier.issn1687-5214
dc.identifier.pmid22611373
dc.identifier.scopus2-s2.0-84861017791
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1155/2012/316384
dc.identifier.urihttps://hdl.handle.net/11468/17860
dc.identifier.wosWOS:000303728200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHindawi Publishing Corporationen_US
dc.relation.ispartofExperimental Diabetes Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleIncreased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Ratsen_US
dc.titleIncreased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats
dc.typeArticleen_US

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