Increased Caspase-3 Immunoreactivity of Erythrocytes in STZ Diabetic Rats
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Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Hindawi Publishing Corporation
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Eryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, it is presented that the majority of erythrocytes shows caspase-3 immunoreactivity in streptozocin- (STZ)-induced diabetic rats. Besides that, caspase-3 positive erythrocytes are aggregated and attached to vascular endothelium. In conclusion, these results may start a debate that eryptosis could have a role in the diabetic complications.
Açıklama
Anahtar Kelimeler
[No Keyword]
Kaynak
Experimental Diabetes Research
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
