A case of refractory polymyositis successfully treated with abatacept monotherapy

dc.authorid0000-0001-9740-5407en_US
dc.contributor.authorÇaǧlayan, Mehmet
dc.contributor.authorIşık, Hüseyin
dc.contributor.authorOktayoǧlu, Pelin
dc.date.accessioned2021-07-27T13:28:44Z
dc.date.available2021-07-27T13:28:44Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalıen_US
dc.descriptionWOS:000595829400019
dc.descriptionPMID: 33758820
dc.description.abstractPolymyositis (PM) is an autoimmune disease progressing in the form of a break down of the muscles that is induced by chronic inflammation in skeletal muscles. Muscle weakness is painless and concentrates on proximal muscles, involving the pectoral and pelvic girdle. If the disease is not treated properly, it may progress and lead to a considerable decrease in the quality of life. Its conventional treatment involves drugs that suppress inflammation such as steroids, methotrexate, azathioprine, and intravenous immunoglobulin. However, conventional treatment may prove insufficient to halt the progression of the disease and offer only a limited improvement because of the adverse effects it causes in some patients. In this article, we present a 48-year-old female patient diagnosed with PM nearly 13 years ago that did not sufficiently respond to the pharmaceutical agents that were indicated for the conventional treatment of the disease and developed femoral head avascular necrosis because of the treatment and was, in the end, successfully treated with abatacept monotherapy at our clinic.en_US
dc.identifier.citationÇaǧlayan, M., Işık, H. ve Oktayoǧlu, P. (2020). A case of refractory polymyositis successfully treated with abatacept monotherapy. Archives of Rheumatology, 35(4), 618-622.en_US
dc.identifier.doi10.46497/ArchRheumatol.2020.7406
dc.identifier.endpage622en_US
dc.identifier.issn2148-5046
dc.identifier.issue4en_US
dc.identifier.pmid33758820
dc.identifier.scopus2-s2.0-85097167104
dc.identifier.scopusqualityQ3
dc.identifier.startpage618en_US
dc.identifier.trdizinid457561
dc.identifier.urihttps://archivesofrheumatology.org/full-text/1127
dc.identifier.urihttps://hdl.handle.net/11468/7243
dc.identifier.volume35en_US
dc.identifier.wosWOS:000595829400019
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorÇaǧlayan, Mehmet
dc.institutionauthorIşık, Hüseyin
dc.institutionauthorOktayoǧlu, Pelin
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatism (TLAR)en_US
dc.relation.ispartofArchives of Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAbatacepten_US
dc.subjectMonotherapyen_US
dc.subjectPolymyositisen_US
dc.titleA case of refractory polymyositis successfully treated with abatacept monotherapyen_US
dc.titleA case of refractory polymyositis successfully treated with abatacept monotherapy
dc.typeArticleen_US

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