Treatment of osteoporosis by long-term magnetic field with extremely low frequency in rats

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dc.contributor.authorAkpolat, Veysi
dc.contributor.authorCelik, Mustafa Salih
dc.contributor.authorCelik, Yusuf
dc.contributor.authorAkdeniz, Nurten
dc.contributor.authorOzerdem, Mehmet Sirac
dc.date.accessioned2024-04-24T16:24:44Z
dc.date.available2024-04-24T16:24:44Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground. Osteoporosis is characterised by low bone mass and structural deterioration of bone tissue. In this study, the role of long-term extremely low frequency magnetic field (ELFMF) on osteoporosis was evaluated. Methods. The experiments were performed on 45 female Sprague-Dawley rats. The rats were divided into three groups (n = 15): Group I ( ovariectomy (OVX) + ELFMF exposure), Group II ( ovariectomised rats did not receive any treatment) and Group III (cage-control). Six months, 50 Hz, 1.5 mT magnetic field (MF) was used on Group I and Group II. Total body images of the animals were obtained with dual-energy X-ray absorptiometry. Results. Bone mineral content (BMC) and bone mineral density values were increased significantly in ELFMF group, decreased in the group of OVX and not changed in cage-control. At the end of the 6 months after exposure with ELFMF, alteration in studied biochemical markers were detected significant. Bone specific alkaline phosphatase (BAP) levels were increased in ELFMF and decreased in OVX groups when compared with cage-control group. N-telopeptide levels in OVX group were significantly higher than other groups. Testosterone and cortisol levels in OVX group were significantly higher and estradiol was lower than other groups. Conclusions. Our study suggests that ELFMF may be useful in the prevention and treatment of osteoporosis.en_US
dc.description.sponsorshipDicle University Research Project Committee [DUAP-02-TF-02]en_US
dc.description.sponsorshipThis study was supported by Dicle University Research Project Committee (DUAP-02-TF-02).en_US
dc.identifier.doi10.1080/09513590902972075
dc.identifier.endpage529en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue8en_US
dc.identifier.pmid19903057
dc.identifier.scopus2-s2.0-70350633730
dc.identifier.scopusqualityQ2
dc.identifier.startpage524en_US
dc.identifier.urihttps://doi.org/10.1080/09513590902972075
dc.identifier.urihttps://hdl.handle.net/11468/16836
dc.identifier.volume25en_US
dc.identifier.wosWOS:000268877800009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofGynecological Endocrinology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOsteoporosisen_US
dc.subjectOvaryen_US
dc.subjectMenopauseen_US
dc.titleTreatment of osteoporosis by long-term magnetic field with extremely low frequency in ratsen_US
dc.titleTreatment of osteoporosis by long-term magnetic field with extremely low frequency in rats
dc.typeArticleen_US

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