Evaluation of clinical and oral findings in patients with epidermolysis bullosa

Basit Öğe Kaydı
dc.authorid0000-0001-6953-747Xen_US
dc.authorid0000-0002-6161-3666en_US
dc.contributor.authorYavuz, Yasemin
dc.contributor.authorAn, İsa
dc.contributor.authorYazmacı, Betül
dc.contributor.authorAkkuş, Zeki
dc.contributor.authorOrtaç, Hatice
dc.date.accessioned2023-09-29T12:18:41Z
dc.date.available2023-09-29T12:18:41Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyoistatistik ve Tıbbi Bilişim Ana Bilim Dalıen_US
dc.description.abstractIntroduction: Epidermolysis bullosa (EB) is a genetically inherited disease characterized by recurrent bullae and erosions on the skin with numerous signs of dental caries and poor oral hygiene. The aim of this study was to investigate the general clinical and oral findings of patients with EB. Materials and Methods: In this prospective study, the clinical and oral findings and family history of 26 cases with EB were evaluated. The type of EB, gender, age, parental consanguinity, dental caries, oral findings, distribution of lesions and presence of associated anomalies, clinical and oral findings correlated with gender were recorded. Results: All 26 patients with EB had a history of consanguinity and siblings with EB to varying degrees. In our study, malnutrition, anemia and growth retardation, gastrointestinal system complications, hair thinning, hand and nail deformity, ocular problems and renal disease (in one case) were observed with variable frequencies. When the intraoral findings of the patients were investigated, extensive dental caries in all EB types, enamel hypoplasia in junctional EB (JEB) and the presence of tooth-root to be extracted in dystrophic EB (DEB), intraoral bullae and lesions, ankyloglossia, vestibular sulcus insufficiency, microstomia and maxillary atrophy were observed. Three cases had restorative treatment and one case had prosthetic rehabilitation. Conclusions: Oral involvement can be seen with varying frequencies depending on the type of EB and the severity of the disease. It may result from delayed oral and dental rehabilitation due to physical disabilities, limitations and more pressing medical problems. Microstomy, pain from mucosal lesions, and restricted access to the mouth can be caused by poor oral hygiene. Oral complications and caloric needs of individuals with EB should be determined, and individual prophylaxis should be applied to prevent caries formation and protect teeth.en_US
dc.identifier.citationYavuz, Y., An, İ., Yazmacı, B., Akkuş, Z., ve Ortaç, H. (2023). Evaluation of clinical and oral findings in patients with epidermolysis bullosa. Medicina (Lithuania), 59(7), 1-11.en_US
dc.identifier.doi10.3390/medicina59071185
dc.identifier.endpage11en_US
dc.identifier.issn1010-660X
dc.identifier.issue7en_US
dc.identifier.pmid37511997
dc.identifier.scopus2-s2.0-85166013566
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.mdpi.com/1648-9144/59/7/1185
dc.identifier.urihttps://hdl.handle.net/11468/12635
dc.identifier.volume59en_US
dc.identifier.wosWOS:001036496700001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAkkuş, Zeki
dc.language.isoenen_US
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)en_US
dc.relation.ispartofMedicina (Lithuania)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpidermolysis bullosaen_US
dc.subjectBullaeen_US
dc.subjectOral hygieneen_US
dc.subjectDental cariesen_US
dc.titleEvaluation of clinical and oral findings in patients with epidermolysis bullosaen_US
dc.titleEvaluation of clinical and oral findings in patients with epidermolysis bullosa
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Evaluation of Clinical and Oral Findings in Patients with Epidermolysis bullosa.pdf
Boyut:
2.37 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Temel Tıp Bilimleri Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu