The investigation of bone-implant connection and new bone formation in fasting and high-fatty diet rats

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dc.authorid0000-0003-3420-5816en_US
dc.authorid0000-0003-2568-7470en_US
dc.contributor.authorYavuz, M. C.
dc.contributor.authorGüler, Rıdvan
dc.contributor.authorÖzcan, Erhan Cahit
dc.contributor.authorBozoğlan, Alihan
dc.contributor.authorKirtay, Mustafa
dc.contributor.authorKaya, C. A.
dc.contributor.authorDündar, Serkan
dc.date.accessioned2024-04-15T12:38:49Z
dc.date.available2024-04-15T12:38:49Z
dc.date.issued2024en_US
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Ağız-Diş-Çene Hastalıkları ve Cerrahisi Bölümüen_US
dc.description.abstractBACKGROUND: Hyperlipidemia caused by a high-fat diet (HFD) has many adverse effects on the cardiovascular system, including vascular problems. In addition, a HFD also has significant adverse effects on bone health. AIM: The aim of this study is to examine bone-implant osteointegration and new bone formation in peri-implant defects in fasting and high-fatty diet applied rats. MATERIALS AND METHODS: In this study, 28 female Sprague Dawley rats were used. The rats were divided into four groups, with seven rats in each group: the control group on a normal diet (Group 1) (n = 7), the fasted group (Group 2) (n = 7), the high-fatty diet (HFD) group (Group 3) (n = 7), and the fasted and HFD group (Group 4) (n = 7). Titanium implants with a diameter of 2.5 mm and a length of 4 mm were placed in the right tibia bones of the subjects, and a bone graft corresponding to 2 mm of the implant length was placed in the bone defect applied to the neck region. All rats that continued the administered diet for 12 weeks were sacrificed at the end of the experiment period. The implants and surrounding bone tissue were surgically removed and subjected to biomechanical analysis to assess bone-implant osteointegration and peri-implant new bone formation. RESULTS: It was determined that there was no statistically significant difference between the rats in the control group and the other three groups in terms of bone-implant osteointegration and peri-implant new bone formation (P > 0.05). CONCLUSION: As a result of this study, it was determined that fasting or maintaining a HFD does not adversely affect bone-implant osteointegration or peri-implant new bone formation in the tibias of rats.en_US
dc.identifier.citationYavuz, M.C., Güler, R., Özcan, E. C., Bozoğlan, A., Kirtay, M., Kaya, C. A. ve diğerleri. (2024). The investigation of bone-implant connection and new bone formation in fasting and high-fatty diet rats. Nigerian Journal of Clinical Practice, 27(1), 95-101.en_US
dc.identifier.doi10.4103/njcp.njcp_530_23
dc.identifier.endpage101en_US
dc.identifier.issn1119-3077
dc.identifier.issue1en_US
dc.identifier.pmid38317041
dc.identifier.scopus2-s2.0-85184400767
dc.identifier.scopusqualityQ2
dc.identifier.startpage95en_US
dc.identifier.urihttps://journals.lww.com/njcp/fulltext/2024/01000/the_investigation_of_bone_implant_connection_and.14.aspx
dc.identifier.urihttps://hdl.handle.net/11468/13872
dc.identifier.volume27en_US
dc.identifier.wosWOS:001158041700022
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGüler, Rıdvan
dc.language.isoenen_US
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectImplant connectionen_US
dc.subjectNew bone formationen_US
dc.subjectHigh-fatty diet ratsen_US
dc.titleThe investigation of bone-implant connection and new bone formation in fasting and high-fatty diet ratsen_US
dc.titleThe investigation of bone-implant connection and new bone formation in fasting and high-fatty diet rats
dc.typeArticleen_US

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