Microbiologic and histologic assessment of intentional bacterial contamination of bone grafts

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dc.contributor.authorYaman, Ferhan
dc.contributor.authorUenlue, Guelten
dc.contributor.authorAtilgan, Serhat
dc.contributor.authorCelik, Yusuf
dc.contributor.authorOezekinci, Tuncer
dc.contributor.authorYaldiz, Mehmet
dc.date.accessioned2024-04-24T16:15:13Z
dc.date.available2024-04-24T16:15:13Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study was to investigate methods of removing pathogenic microorganisms from bone grafts that have been contaminated during surgery. Materials and Methods: Femora were removed from Sprague-Dawley rats and were divided into sections and contaminated in solutions of the bacteria Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Contaminated bone specimens in each group were immersed in various solutions for specified periods so their antibacterial effects could be evaluated. After these procedures were performed, bone specimens were cultured in nutrient media. Bone structure was evaluated, and the appropriate decontamination method was selected. Results: Solutions such as povidone-iodine, neomycin, cephazolin sodium, and rifamycin were found to be effective decontaminants. These solutions did not damage the bone structure. Among these solutions, only rifamycin was effective against all bacteria used in this study to contaminate bone grafts. Conclusions: Rifamycin seems to be the most suitable agent for the elimination of contamination introduced into bone grafts during surgery. (c) 2007 American Association of Oral and Maxillofacial Surgeons.en_US
dc.identifier.doi10.1016/j.joms.2006.10.027
dc.identifier.endpage1494en_US
dc.identifier.issn0278-2391
dc.identifier.issn1531-5053
dc.identifier.issue8en_US
dc.identifier.pmid17656273en_US
dc.identifier.scopus2-s2.0-34447552503en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1490en_US
dc.identifier.urihttps://doi.org/10.1016/j.joms.2006.10.027
dc.identifier.urihttps://hdl.handle.net/11468/15708
dc.identifier.volume65en_US
dc.identifier.wosWOS:000248706000009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofJournal of Oral and Maxillofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleMicrobiologic and histologic assessment of intentional bacterial contamination of bone graftsen_US
dc.typeArticleen_US

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