Microbiologic and histologic assessment of intentional bacterial contamination of bone grafts
[ X ]
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
W B Saunders Co-Elsevier Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: The purpose of this study was to investigate methods of removing pathogenic microorganisms from bone grafts that have been contaminated during surgery. Materials and Methods: Femora were removed from Sprague-Dawley rats and were divided into sections and contaminated in solutions of the bacteria Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Contaminated bone specimens in each group were immersed in various solutions for specified periods so their antibacterial effects could be evaluated. After these procedures were performed, bone specimens were cultured in nutrient media. Bone structure was evaluated, and the appropriate decontamination method was selected. Results: Solutions such as povidone-iodine, neomycin, cephazolin sodium, and rifamycin were found to be effective decontaminants. These solutions did not damage the bone structure. Among these solutions, only rifamycin was effective against all bacteria used in this study to contaminate bone grafts. Conclusions: Rifamycin seems to be the most suitable agent for the elimination of contamination introduced into bone grafts during surgery. (c) 2007 American Association of Oral and Maxillofacial Surgeons.
Açıklama
Anahtar Kelimeler
[No Keyword]
Kaynak
Journal of Oral and Maxillofacial Surgery
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
65
Sayı
8
