Myocardial Performance Index for Patients with Overt and Subclinical Hypothyroidism

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dc.contributor.authorKarabulut, Aziz
dc.contributor.authorDogan, Abdullah
dc.contributor.authorTuzcu, Alparslan Kemal
dc.date.accessioned2024-04-24T17:15:07Z
dc.date.available2024-04-24T17:15:07Z
dc.date.issued2017
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Hypothyroid has several effects on the cardiovascular system. Global myocardial performance index (MPI) is used in assessment of both left ventricular (LV) systolic and diastolic function. We compared MPI in hypothyroidism patients vs. normal control subjects. Material/Methods: Eighty-two hypothyroid patients were divided into 2 groups: a subclinical hypothyroid (SH) group (n=50), and an overt hypothyroid (OH) group (n=32). The healthy control group (CG) constituted of 37 patients. TSH, FT3, and FT4, anti-TPO, anti-TG, insulin, lipid values, and fasting glucose levels were studied. All patients underwent an echocardiographic examination. Myocardial performance indexes were assessed and standard echocardiographic examinations were investigated. Results: MPI averages in OH, SH, and control groups were 0.53 +/- 0.06, 0.51 +/- 0.05, and 0.44 +/- 0.75 mm, respectively. MPI was increased in the OH and SH groups in comparison to CG (p < 0.001, p < 0.001, respectively). Conclusions: MPI value was significantly higher in hypothyroid patients in comparison to the control group, showing that regression in global left ventricular functions is an important echocardiographic finding. Future studies are required to determine the effects of this finding on long-term cardiovascular outcomes.en_US
dc.identifier.doi10.12659/MSM.905190
dc.identifier.endpage2526en_US
dc.identifier.issn1643-3750
dc.identifier.pmid28540919en_US
dc.identifier.scopus2-s2.0-85020209639en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage2519en_US
dc.identifier.urihttps://doi.org/10.12659/MSM.905190
dc.identifier.urihttps://hdl.handle.net/11468/18344
dc.identifier.volume23en_US
dc.identifier.wosWOS:000402014400002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInt Scientific Literature, Incen_US
dc.relation.ispartofMedical Science Monitoren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiovascular Abnormalitiesen_US
dc.subjectEchocardiographyen_US
dc.subjectHypothyroidismen_US
dc.titleMyocardial Performance Index for Patients with Overt and Subclinical Hypothyroidismen_US
dc.typeArticleen_US

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