Myocardial Performance Index for Patients with Overt and Subclinical Hypothyroidism
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Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Int Scientific Literature, Inc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Hypothyroid has several effects on the cardiovascular system. Global myocardial performance index (MPI) is used in assessment of both left ventricular (LV) systolic and diastolic function. We compared MPI in hypothyroidism patients vs. normal control subjects. Material/Methods: Eighty-two hypothyroid patients were divided into 2 groups: a subclinical hypothyroid (SH) group (n=50), and an overt hypothyroid (OH) group (n=32). The healthy control group (CG) constituted of 37 patients. TSH, FT3, and FT4, anti-TPO, anti-TG, insulin, lipid values, and fasting glucose levels were studied. All patients underwent an echocardiographic examination. Myocardial performance indexes were assessed and standard echocardiographic examinations were investigated. Results: MPI averages in OH, SH, and control groups were 0.53 +/- 0.06, 0.51 +/- 0.05, and 0.44 +/- 0.75 mm, respectively. MPI was increased in the OH and SH groups in comparison to CG (p < 0.001, p < 0.001, respectively). Conclusions: MPI value was significantly higher in hypothyroid patients in comparison to the control group, showing that regression in global left ventricular functions is an important echocardiographic finding. Future studies are required to determine the effects of this finding on long-term cardiovascular outcomes.
Açıklama
Anahtar Kelimeler
Cardiovascular Abnormalities, Echocardiography, Hypothyroidism
Kaynak
Medical Science Monitor
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
23
