Growth hormone stimulation tests in chronic renal failure with metabolic acidosis

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dc.contributor.authorBircan, Z
dc.contributor.authorKervancioglu, M
dc.contributor.authorSoran, M
dc.contributor.authorYildirim, I
dc.date.accessioned2024-04-24T17:37:29Z
dc.date.available2024-04-24T17:37:29Z
dc.date.issued1998
dc.departmentDicle Üniversitesien_US
dc.description.abstractMetabolic acidosis is one of the possible causes of growth retardation in chronic renal failure (CRF). Data about the effect of metabolic acidosis on growth hormone (GPI) secretion in CRF are limited. A study was carried out on eight CRF patients, hospitalized because of severe metabolic acidosis, and eight age-matched prepubertal healthy short children. Growth hormone stimulation tests were done with L-dopa and clonidine before or during acidosis therapy and after the correction of metabolic acidosis. The levels of GH were measured by radio-immunoassay. The mean of the peaks of both tests were used for each patient and statistical significance was tested by Mann-Whitney U and Wilcoxon tests. No difference was found between the GH peaks of the two groups during acidosis and after the correction of acidosis (Wilcoxon test, P > 0.05). In view of this data it was concluded that metabolic acidosis has little effect on GH stimulation tests.en_US
dc.identifier.endpage72en_US
dc.identifier.issn0374-5600
dc.identifier.issue1en_US
dc.identifier.pmid9583205
dc.identifier.scopus2-s2.0-0031934525
dc.identifier.scopusqualityN/A
dc.identifier.startpage70en_US
dc.identifier.urihttps://hdl.handle.net/11468/20945
dc.identifier.volume40en_US
dc.identifier.wosWOS:000073162300014
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBlackwell Publishing Asiaen_US
dc.relation.ispartofActa Paediatrica Japonica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic Renal Failureen_US
dc.subjectGrowth Hormoneen_US
dc.subjectMetabolic Acidosisen_US
dc.titleGrowth hormone stimulation tests in chronic renal failure with metabolic acidosisen_US
dc.titleGrowth hormone stimulation tests in chronic renal failure with metabolic acidosis
dc.typeArticleen_US

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