The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19
dc.authorid | 0000-0001-6560-5746 | en_US |
dc.contributor.author | Işık, Ferhat | |
dc.contributor.author | Çap, Murat | |
dc.contributor.author | Akyüz, Abdurrahman | |
dc.contributor.author | Bilge, Önder | |
dc.contributor.author | Aslan, Burhan | |
dc.contributor.author | İnci, Ümit | |
dc.contributor.author | Kaya, İlyas | |
dc.contributor.author | Taştan, Ercan | |
dc.contributor.author | Okşul, Metin | |
dc.contributor.author | Çap, Neşe Kanbal | |
dc.contributor.author | Karagöz, Ali | |
dc.contributor.author | Baysal, Erkan | |
dc.date.accessioned | 2021-08-19T12:48:26Z | |
dc.date.available | 2021-08-19T12:48:26Z | |
dc.date.issued | 2021 | en_US |
dc.department | Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalı | en_US |
dc.description | WOS:000681541900001 | |
dc.description | PMID34354253 | |
dc.description.abstract | Hypertension is a major concomitant disease in hospitalized patients with COVID-19 (Coronavirus disease 2019) infection. The adverse effect of hypertension on prognosis in COVID-19 is known. Nevertheless, it is not known how COVID-19 progresses in resistant hypertensive patients. In this study, we aimed to examine the effect of resistant hypertension (ResHT) on in-hospital mortality in patients hospitalized with COVID-19. In our single-center retrospective study, included 1897 COVID-19 patients. The patients were divided into three groups according to the non-hypertensive (n = 1211), regulated HT (RegHT) (n = 574), and ResHT (n = 112). These three groups were compared according to demographic features, clinical signs, laboratory findings, and follow-up times. The median age of the study population was 62 (50–72 IQR) and 1000 (52.7%) of patients were male. The total mortality of the study population was 18.7% (n = 356). Mortality rates were similar in the hypertensive patient group (27.5% for the RegHT and 32.1% for ResHT, p = 0.321). In a multivariable analysis, ResHT was independently associated with a significantly increased risk of inhospital mortality of COVID-19, while no significant increased risk was observed with RegHT [respectively, Odds Ratio (OR) = 2.013, Confidence Interval (CI) 1.085–3.734, p = 0.026 and OR = 1.194, CI 0.795–1.794, p = 0.394]. Also, age, male gender, chronic renal failure, lymphocyte, procalcitonin, creatinine, and admission SpO2 levels were determined as independent predictors of in-hospital mortality. In our study, it was found that ResHT was an independent predictor of mortality in patients hospitalized with COVID-19; however, this situation was not found in RegHT. | en_US |
dc.identifier.citation | Işık, F., Çap, M., Akyüz, A., Bilge, Ö., Aslan, B., İnci, Ü. ve diğerleri. (2021). The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19. Journal of Human Hypertension, Early Access | en_US |
dc.identifier.doi | 10.1038/s41371-021-00591-8 | |
dc.identifier.endpage | 6 | en_US |
dc.identifier.issn | 0950-9240 | |
dc.identifier.issn | 1476-5527 | |
dc.identifier.pmid | 34354253 | |
dc.identifier.scopus | 2-s2.0-85111904644 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 1 | en_US |
dc.identifier.uri | https://www.nature.com/articles/s41371-021-00591-8.pdf | |
dc.identifier.uri | https://hdl.handle.net/11468/7361 | |
dc.identifier.volume | Early Access | en_US |
dc.identifier.wos | WOS:000681541900001 | |
dc.identifier.wosquality | Q3 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.institutionauthor | Çap, Neşe Kanbal | |
dc.language.iso | en | en_US |
dc.publisher | Springer Nature | en_US |
dc.relation.ispartof | Journal of Human Hypertension | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Hypertension | en_US |
dc.subject | Hipertansiyon | en_US |
dc.subject | COVID-19 | en_US |
dc.title | The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19 | en_US |
dc.title | The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19 | |
dc.type | Article | en_US |
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