The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19
Yükleniyor...
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Nature
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Hypertension is a major concomitant disease in hospitalized patients with COVID-19 (Coronavirus disease 2019) infection. The
adverse effect of hypertension on prognosis in COVID-19 is known. Nevertheless, it is not known how COVID-19 progresses in
resistant hypertensive patients. In this study, we aimed to examine the effect of resistant hypertension (ResHT) on in-hospital
mortality in patients hospitalized with COVID-19. In our single-center retrospective study, included 1897 COVID-19 patients. The
patients were divided into three groups according to the non-hypertensive (n = 1211), regulated HT (RegHT) (n = 574), and ResHT
(n = 112). These three groups were compared according to demographic features, clinical signs, laboratory findings, and follow-up
times. The median age of the study population was 62 (50–72 IQR) and 1000 (52.7%) of patients were male. The total mortality of
the study population was 18.7% (n = 356). Mortality rates were similar in the hypertensive patient group (27.5% for the RegHT and
32.1% for ResHT, p = 0.321). In a multivariable analysis, ResHT was independently associated with a significantly increased risk of inhospital mortality of COVID-19, while no significant increased risk was observed with RegHT [respectively, Odds Ratio (OR) = 2.013,
Confidence Interval (CI) 1.085–3.734, p = 0.026 and OR = 1.194, CI 0.795–1.794, p = 0.394]. Also, age, male gender, chronic renal
failure, lymphocyte, procalcitonin, creatinine, and admission SpO2 levels were determined as independent predictors of in-hospital
mortality. In our study, it was found that ResHT was an independent predictor of mortality in patients hospitalized with COVID-19;
however, this situation was not found in RegHT.
Açıklama
WOS:000681541900001
PMID34354253
PMID34354253
Anahtar Kelimeler
Hypertension, Hipertansiyon, COVID-19
Kaynak
Journal of Human Hypertension
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
Early Access
Sayı
Künye
Işık, F., Çap, M., Akyüz, A., Bilge, Ö., Aslan, B., İnci, Ü. ve diğerleri. (2021). The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19. Journal of Human Hypertension, Early Access
