Exchange transfusion for neonatal hyperbilirubinemia: A multicenter, prospective study of Turkish Neonatal Society

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dc.authorid0000-0003-0903-6520en_US
dc.contributor.authorOkulu, Emel
dc.contributor.authorErdeve, Ömer
dc.contributor.authorTuncer, Oguz
dc.contributor.authorErtuğrul, Sabahattin
dc.contributor.authorÖzdemir, Hülya
dc.contributor.authorÇiftdemir, Nükhet Aladağ
dc.contributor.authorZenciroğlu, Ayşegül
dc.contributor.authorAtasay, Begüm
dc.date.accessioned2022-06-17T12:11:50Z
dc.date.available2022-06-17T12:11:50Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.descriptionWOS:000624295100005
dc.descriptionPMID: 34286320
dc.description.abstractAbstract Objective: The frequency of neonatal exchange transfusion has declined in recent years, but is still performed in many countries. The procedure is associated with complications. The aim of the study was to determine the clinical features and etiologies of infants with hyperbilirubinemia who underwent exchange transfusion and evaluate the adverse events and clinical outcomes. Material and Methods: We performed a secondary analysis of the multicenter Turkish Neonatal Jaundice Online Registry data. Otherwise healthy newborns born >= 35 weeks of gestation who were hospitalized for jaundice and underwent exchange transfusion were included. Results: One-hundred thirty-two patients with a mean serum bilirubin level on admission of 24.9 +/- 9.1 mg/dL were enrolled in the study. The most common cause for exchange transfusion was hemolytic jaundice (63.6%), followed by lack of proper feeding (12.9%). It was found that the infants with lack of proper feeding were discharged earlier from the maternity ward (p=0.02), but they were admitted to hospital later (p<0.001) with a higher bilirubin level (p=0.001), and geater weight loss (p=0.04). The reported rate of adverse events associated with exchange transfusion was 11.4%. The most common complication was thrombocytopenia (40%). None of the infants died during the procedure. Acute bilirubin encephalopathy was reported in 13 (9.8%) patients. Conclusion: Severe hyperbilirubinemia requiring exchange transfusion and acute bilirubin encephalopathy are still challenging problems in neonatal periodin our country. The policies including blood group analysis of pregnant women, programs informing parents about breast-feeding and jaundice, and monitoring bilirubin levels of high-risk newborns should be developed to reduce the necessitating for exchange transfusion and to avoid related complications.en_US
dc.identifier.citationOkulu, E., Erdeve, Ö., Tuncer, O., Ertuğrul, S., Özdemir, H., Çiftdemir, N.A. ve diğerleri. (2021). Exchange transfusion for neonatal hyperbilirubinemia: A multicenter, prospective study of Turkish Neonatal Society. Turkish Archives Pediatrics, 56(2), 121-126.en_US
dc.identifier.doi10.14744/TurkPediatriArs.2020.65983
dc.identifier.endpage126en_US
dc.identifier.issn2757-6256
dc.identifier.issue2en_US
dc.identifier.pmid34286320
dc.identifier.scopus2-s2.0-85118905003
dc.identifier.scopusqualityQ3
dc.identifier.startpage121en_US
dc.identifier.trdizinid445503
dc.identifier.urihttps://turkarchpediatr.org//en/exchange-transfusion-for-neonatal-hyperbilirubinemia-a-multicenter-prospective-study-of-turkish-neonatal-society-131195
dc.identifier.urihttps://hdl.handle.net/11468/10020
dc.identifier.volume56en_US
dc.identifier.wosWOS:000624295100005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorErtuğrul, Sabahattin
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Archives Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectComplicationen_US
dc.subjectExchange transfusionen_US
dc.subjectHyperbilirubinemiaen_US
dc.subjectNewbornen_US
dc.titleExchange transfusion for neonatal hyperbilirubinemia: A multicenter, prospective study of Turkish Neonatal Societyen_US
dc.titleExchange transfusion for neonatal hyperbilirubinemia: A multicenter, prospective study of Turkish Neonatal Society
dc.typeArticleen_US

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