A New and Practical Aspartate Aminotransferase Test in Vaginal Washing Fluid for the Detection of Preterm Premature Rupture of Membranes

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dc.contributor.authorKale, Ebru
dc.contributor.authorKuyumcuoglu, Umur
dc.contributor.authorKale, Ahmet
dc.contributor.authorGuezel, Ali Irfan
dc.contributor.authorCanoruc, Naime
dc.date.accessioned2024-04-24T17:14:27Z
dc.date.available2024-04-24T17:14:27Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives: To determine whether measurement of aspartate aminotransferase (Ast) and alanine aminotransferase (Alt) levels in vaginal fluid is useful for the diagnosis of preterm premature rupture of membranes (PPROM). Study Design: The PPROM group and normal pregnancy group consisted of 36 and 48 pregnant patients between 26 and 36 weeks' gestation, respectively. Vaginal fluid Ast and Alt levels were measured in both groups. Results: Vaginal fluid Alt level was not statistically significant in the PPROM group as compared with the control group (p = 0.064). Vaginal Ast level was statistically significant in the PPROM (14.4 +/- 17.46 U/l) group as compared with the control group (3.08 +/- 7.8 U/l; p = 0.001). The optimal cutoff value of 3 IU/l for Ast gave a sensitivity level of 91% at a specificity of 83%, with positive and negative predictive values of 80 and 93%, respectively. Conclusion: Ast measurement from vaginal washing fluid appears to be a useful marker for the detection of PPROM. Copyright (C) 2008 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000170093
dc.identifier.endpage428en_US
dc.identifier.issn1015-3837
dc.identifier.issn1421-9964
dc.identifier.issue4en_US
dc.identifier.pmid18987481
dc.identifier.scopus2-s2.0-55149100253
dc.identifier.scopusqualityQ1
dc.identifier.startpage425en_US
dc.identifier.urihttps://doi.org/10.1159/000170093
dc.identifier.urihttps://hdl.handle.net/11468/17955
dc.identifier.volume24en_US
dc.identifier.wosWOS:000262548200023
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofFetal Diagnosis and Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPreterm Premature Rupture Of Membranesen_US
dc.subjectAspartate Aminotransferaseen_US
dc.subjectAlanine Aminotransferaseen_US
dc.titleA New and Practical Aspartate Aminotransferase Test in Vaginal Washing Fluid for the Detection of Preterm Premature Rupture of Membranesen_US
dc.titleA New and Practical Aspartate Aminotransferase Test in Vaginal Washing Fluid for the Detection of Preterm Premature Rupture of Membranes
dc.typeArticleen_US

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