A retrospective evaluation of geriatric patients with gastric cancer receiving systemic chemotherapy

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dc.authorid0000-0003-3878-988Xen_US
dc.contributor.authorTatlı, Ali Murat
dc.contributor.authorUrakçı, Zuhat
dc.contributor.authorTaştekin, Didem
dc.contributor.authorKoca, Doǧan
dc.contributor.authorGöksu, Sema Sezgin
dc.contributor.authorÜyetürk, Ümmügül
dc.contributor.authorKaplan, Mehmet Ali
dc.contributor.authorÇoşkun, Hasan Şenol
dc.date.accessioned2021-04-21T10:25:07Z
dc.date.available2021-04-21T10:25:07Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyasyon OnkolojisiAna Bilim Dalıen_US
dc.descriptionPMID: 33380668
dc.descriptionWOS:000612861200024
dc.description.abstractBackground: The most common age at which gastric cancer is diagnosed is 70 years, and the majority of patients diagnosed are at the metastatic stage. However, although gastric cancer is a geriatric disease, there is no suggestion to discriminate treatment for the general geriatric patient population. Here, we evaluated patients receiving palliative chemotherapy for gastric cancer owing to advanced age. Patients and Methods: Multicenter data of geriatric patients receiving palliative chemotherapy because of metastatic gastric cancer were retrospectively reviewed. Results: In total, 262 geriatric patients with gastric cancer were included in the study. Of these, 167 patients, including 134 (51.8%) patients with metastasis at diagnosis and 33 patients with relapse after surgery, were evaluated for palliative therapy. Chemotherapy was started in 87 (52.1%) of 167 patients. The overall median survival of the patients receiving chemotherapy was 9.3 months. There was no difference in overall survival (OS) between patients aged >70 and <70 years. However, a significant difference was detected in OS of patients depending on their Eastern Cooperative Oncology Group (ECOG) performance status(PS) before treatment; survival was 15 months in the group with PS 0–1 and 7 months in the group with PS ≥2. Conclusion: Advanced age chemotherapy receiving rates in patients with metastatic gastric cancer is decreasing. Survival is not associated with age, but pretreatment ECOG PS is important. Therefore, ECOG PS and comorbidities should be evaluated in detail, and combination therapies could contribute to patient survival.en_US
dc.identifier.citationTatlı, A. M., Urakçı, Z., Taştekin, D., Koca, D., Göksu, S. S., Üyetürk, Ü. ve diğerleri. (2020). A retrospective evaluation of geriatric patients with gastric cancer receiving systemic chemotherapy. Journal of Cancer Research and Therapeutics, 16(8), 138-143.en_US
dc.identifier.doi10.4103/jcrt.JCRT_563_18
dc.identifier.endpage143en_US
dc.identifier.issn0973-1482
dc.identifier.issn0974-1127
dc.identifier.issue8en_US
dc.identifier.pmid33380668
dc.identifier.scopus2-s2.0-85098942676
dc.identifier.scopusqualityQ3
dc.identifier.startpage138en_US
dc.identifier.urihttps://www.cancerjournal.net/temp/JCanResTher168138-4328517_120125.pdf
dc.identifier.urihttps://hdl.handle.net/11468/6788
dc.identifier.volume16en_US
dc.identifier.wosWOS:000612861200024
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorUrakçı, Zuhat
dc.institutionauthorKaplan, Mehmet Ali
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofJournal of Cancer Research and Therapeutics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGeriatric patientsen_US
dc.subjectMetastatic gastric canceren_US
dc.subjectSystemic chemotherapyen_US
dc.titleA retrospective evaluation of geriatric patients with gastric cancer receiving systemic chemotherapyen_US
dc.titleA retrospective evaluation of geriatric patients with gastric cancer receiving systemic chemotherapy
dc.typeArticleen_US

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