Phytochemical profiling and biological activity of Achillea sintenisii Hub.-Mor

Basit Öğe Kaydı
dc.authorid0000-0002-4674-7009en_US
dc.authorid0000-0003-0101-9742en_US
dc.authorid0000-0001-5700-2419en_US
dc.authorid0000-0003-3994-6576en_US
dc.authorid0000-0002-6504-2223en_US
dc.authorid0000-0003-3118-1054en_US
dc.authorid0000-0002-4090-7227en_US
dc.contributor.authorEruygur, Nuraniye
dc.contributor.authorBüyükyıldırım, Tuğsen
dc.contributor.authorRama, Şeyma Tetik
dc.contributor.authorAyaz, Fatma
dc.contributor.authorTekin, Mehmet
dc.contributor.authorTuzcu, Mehmet
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.date.accessioned2023-10-09T13:04:22Z
dc.date.available2023-10-09T13:04:22Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractAchillea (Asteraceae) species have been traditionally used for their different therapeutical properties. In this study, phytochemical composition of aerial parts of A. sintenisii which is endemic in Turkey was determined with Liquid chromatography/mass spectrometry/mass spectrometry (LC/MS/MS). To evaluate the wound healing potential, the cream formulation prepared from A. sintenisii was tested on the linear incision wound model in mice. In vitro enzyme inhibitory activity tests were performed on elastase, hyaluronidase, and collagenase. In the histopathological examination, angiogenesis and granulation tissue formation were significantly increased in A. sintenisii treatment groups compared to the negative control group. As a result of this study, it is thought that the enzyme inhibition and antioxidant activity of the plant may contribute to the wound healing process. According to LC/MS/MS analysis result, quinic acid (24.261 μg/mg extract) and chlorogenic acid (14.97 μg/mg extract) were identified as main constituents of the extract.en_US
dc.identifier.citationEruygur, N., Büyükyıldırım, T., Rama, Ş. T., Ayaz, F., Tekin, M., Tuzcu, M. ve diğerleri. (2023). Phytochemical profiling and biological activity of Achillea sintenisii Hub.-Mor. Chemistry and Biodiversity, 20(6), 1-9.en_US
dc.identifier.doi10.1002/cbdv.202201258
dc.identifier.endpage9en_US
dc.identifier.issn1612-1872
dc.identifier.issue6en_US
dc.identifier.pmid37203434
dc.identifier.scopus2-s2.0-85159642321
dc.identifier.scopusqualityQ3
dc.identifier.startpage1en_US
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/cbdv.202201258
dc.identifier.urihttps://hdl.handle.net/11468/12776
dc.identifier.volume20en_US
dc.identifier.wosWOS:000990200400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.relation.ispartofChemistry and Biodiversity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAchilleaen_US
dc.subjectPhytochemicalsen_US
dc.subjectAntioxidanten_US
dc.subjectChlorogenic aciden_US
dc.titlePhytochemical profiling and biological activity of Achillea sintenisii Hub.-Moren_US
dc.titlePhytochemical profiling and biological activity of Achillea sintenisii Hub.-Mor
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.-Mor.pdf
Boyut:
614.17 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Eczacılık Fakültesi Temel Eczacılık Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu