The Role of Duration of Hyperbaric Oxygen Therapy on Lung Injury: An Experimental Study Lung Injury and Hyperbaric Oxygen Therapy

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dc.contributor.authorOruc, Menduh
dc.contributor.authorEsen, Bennur
dc.contributor.authorTaylan, Masuk
dc.contributor.authorNergis, Yusuf
dc.contributor.authorSahin, Atalay
dc.date.accessioned2024-04-24T17:27:32Z
dc.date.available2024-04-24T17:27:32Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVES: We aim to histopathologically analyze the effect of hyperbaric oxygen (HBO) therapy in the lung tissue. MATERIAL AND METHODS: A total of 21 rabbits were divided into three groups, with each containing seven rabbits. Group 1 was the control group. Group 2 underwent HBO of 3 atmosphere absolute (ATA) for 90 min/day for 7 days. In group 3, HBO at 3 ATA was administered 90 min/day for 28 days. Oxygen saturation (SpO(2)) was determined by pulse oximetry before and after administration of HBO. Rabbits were sacrificed, and the apex of the right lung was excised. RESULTS: SpO(2) was 98-100% in all rabbits before HBO administration. After the procedure, the mean SpO(2) was 92% and 83% in groups 2 and 3, respectively. As expected, histopathologic examination in group 1 was normal. In group 2, congestion in the lung vessels, mononuclear cell infiltration in the bronchial mucosa, interstitial edema, and alveolar dilation were evident. Histopathologic examination in group 3 indicated diffuse alveolar edema, peribronchial mononuclear cell infiltration, thickening of the alveolar and vessel wall, and intraalveolar hemorrhage. CONCLUSION: There is a strict relationship between duration of HBO administration and severity of lung injury.en_US
dc.identifier.doi10.5152/TurkThoracJ.2018.17060
dc.identifier.endpage65en_US
dc.identifier.issn1302-7808
dc.identifier.issn1308-5387
dc.identifier.issue2en_US
dc.identifier.pmid29755808
dc.identifier.scopus2-s2.0-85045895543
dc.identifier.scopusqualityQ4
dc.identifier.startpage61en_US
dc.identifier.trdizinid305092
dc.identifier.urihttps://doi.org/10.5152/TurkThoracJ.2018.17060
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/305092
dc.identifier.urihttps://hdl.handle.net/11468/20032
dc.identifier.volume19en_US
dc.identifier.wosWOS:000436167400003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBilimsel Tip Publishing Houseen_US
dc.relation.ispartofTurkish Thoracic Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHyperbaric Oxygen Therapyen_US
dc.subjectLung Injuryen_US
dc.subjectBlood Oxygen Saturationen_US
dc.titleThe Role of Duration of Hyperbaric Oxygen Therapy on Lung Injury: An Experimental Study Lung Injury and Hyperbaric Oxygen Therapyen_US
dc.titleThe Role of Duration of Hyperbaric Oxygen Therapy on Lung Injury: An Experimental Study Lung Injury and Hyperbaric Oxygen Therapy
dc.typeArticleen_US

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