Solvent-free synthesis of chiral Schiff-base ligands based on ferrocene under microwave irradiation and application to enantioselective nitroaldol (Henry) reaction
Yükleniyor...
Tarih
2011
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Chiral Schiff-bases 3a-f based on ferrocene were designed and synthesized using solvent-free methods by mixing ferrocene carbaldehyde 1 with amino alcohols and amines 2a-f under microwave irradiation and classical method for the enantioselective nitroaldol (Henry) reaction. The Schiff-bases were obtained in shorter reaction times and improved yield under microwave irradiation method over classical method. The highest enantioselectivity was observed in ligand 3e (95% ee) when CH2Cl2 was used as solvent. Chirality 23: 374-378, 2011. (c) 2011 Wiley-Liss, Inc.
Açıklama
Anahtar Kelimeler
Ferrocene, Microwave irradiation, Chiral schiff-bases, Nitro aldol reaction, Henry reaction
Kaynak
Chirality
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
23
Sayı
5
Künye
Öztürk, G., Çolak, M. ve Demirel, N. (2011). Solvent-free synthesis of chiral Schiff-base ligands based on ferrocene under microwave irradiation and application to enantioselective nitroaldol (Henry) reaction. Chirality, 23(5), 374-378.
