The effects of mucosal media on some pathogenic traits of Crohn's disease-associated Escherichia coli LF82

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dc.contributor.authorAygun, Husamettin
dc.contributor.authorKaramese, Murat
dc.contributor.authorOzic, Cem
dc.contributor.authorUyar, Fikret
dc.date.accessioned2024-04-24T17:18:40Z
dc.date.available2024-04-24T17:18:40Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Adherent-invasive Escherichia coli (AIEC) pathovar has been identified in intestinal mucosa of patients with Crohn's disease. Our aim was to compare the impact of sterile mucosal media (Muc-M) originated from different parts of the intestine on some pathogenic traits of AIEC LF82 strain. Materials & methods: Muc-M composed of certain rates of cell culture medium or M63 minimal medium and mucosal contents obtained from different part of intestine were designed for cell-infection experiments and biofilm-formation assays. Results: The results showed that Muc-M reduced usually pathogenic properties of AIEC LF82. However, LF82 adhesion, invasion and specific biofilm formations were markedly higher in Muc-MCR than those in Muc-MIR. Conclusion: In this context, the findings of present study could help the endeavors related to determining molecular targets for AIEC bacteria.en_US
dc.description.sponsorshipDicle University Coordinatorship of Scientific Research Projects, DUBAP [FEN. 15.002]en_US
dc.description.sponsorshipThis study was supported by the Dicle University Coordinatorship of Scientific Research Projects, DUBAP (FEN. 15.002). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.en_US
dc.identifier.doi10.2217/fmb-2017-0133
dc.identifier.endpage149en_US
dc.identifier.issn1746-0913
dc.identifier.issn1746-0921
dc.identifier.issue2en_US
dc.identifier.pmid29302998
dc.identifier.scopus2-s2.0-85049065053
dc.identifier.scopusqualityQ2
dc.identifier.startpage141en_US
dc.identifier.urihttps://doi.org/10.2217/fmb-2017-0133
dc.identifier.urihttps://hdl.handle.net/11468/18865
dc.identifier.volume13en_US
dc.identifier.wosWOS:000427273500002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherFuture Medicine Ltden_US
dc.relation.ispartofFuture Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdhesionen_US
dc.subjectBiofilmen_US
dc.subjectCrohn's Diseaseen_US
dc.subjectEscherichia Coli Lf82en_US
dc.subjectInvasionen_US
dc.subjectPathobionten_US
dc.titleThe effects of mucosal media on some pathogenic traits of Crohn's disease-associated Escherichia coli LF82en_US
dc.titleThe effects of mucosal media on some pathogenic traits of Crohn's disease-associated Escherichia coli LF82
dc.typeArticleen_US

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