Examination of the effects of COVID 19 on corneal endothelium

dc.authorid0000-0001-5742-1293en_US
dc.authorid0000-0002-8206-781Xen_US
dc.authorid0000-0002-3591-721Xen_US
dc.authorid0000-0001-8856-0528en_US
dc.authorid0000-0003-3346-3290en_US
dc.authorid0000-0003-2348-4856en_US
dc.contributor.authorErdem, Seyfettin
dc.contributor.authorKarahan, Mine
dc.contributor.authorAva, Sedat
dc.contributor.authorDursun, Mehmet Emin
dc.contributor.authorHazar, Leyla
dc.contributor.authorKeklikçi, Uğur
dc.date.accessioned2021-06-18T12:15:37Z
dc.date.available2021-06-18T12:15:37Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.descriptionWOS:000658679800005
dc.descriptionPMID: 34097111
dc.description
dc.description.abstractPurpose To demonstrate the efects of the disease on the corneal endothelium in individuals recovering from COVID-19 through specular microscopy. Methods Eighty individuals recovering from COVID-19 (group 1) and 72 healthy controls (group 2) were included in this prospective study. After examining visual acuity, refractive defect detection, anterior and posterior segment examinations, and specular microscopy measurements were calculated from images with at least 100 cells. The mean cell density (CD), mean coefcient of variation (CV), mean hexagonal cell percentage, mean cell area (AVG), and central corneal thickness (CCT) were evaluated. Results The mean time from diagnosis of the disease in group 1 was 54.25±6.36 days. The mean time elapsed since the PCR test became negative was 38.45±6.87 days. Only four were treated in the hospital. Specular microscopy data showed that the CD was 2713.56±246.25 and 2845.80±299.27 in groups 1 and 2, respectively (p=0.003). The CV values were 42.92±6.79 and 40.16±5.97, respectively (p=0.009). The hexagonality were 46.51±7.35 and 49.12±6.87, respectively (p=0.024). The AVG was 371.60±34.64 and 353.16±35.29, respectively (p=0.007). The CCT values were 553.00±73.2, and 526.84±33.57, respectively (p=0.005). Conclusion A decrease in the number of endothelial cells and hexagonal cells (polymorphism) as well as an increase in the cell area change coefcient (polymegatism) and the average cell area were observed from corneal specular microscopic examination of individuals recovering from COVID-19 in the early period of the disease. These results may be important in understanding the systemic efects of the diseaseen_US
dc.identifier.citationErdem, S., Karahan, M., Ava, S., Dursun, M.E., Hazar, L. ve Keklikçi, U. (2021). Examination of the effects of COVID 19 on corneal endothelium. Graefe’s Archive for Clinical and Experimental Ophthalmology, Early access.en_US
dc.identifier.doi10.1007/s00417-021-05259-0
dc.identifier.issn0721-832X
dc.identifier.issn1435-702X
dc.identifier.pmid34097111
dc.identifier.scopus2-s2.0-85107722177
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://link.springer.com/content/pdf/10.1007/s00417-021-05259-0.pdf
dc.identifier.urihttps://hdl.handle.net/11468/7132
dc.identifier.volumeEarly Accessen_US
dc.identifier.wosWOS:000658679800005
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErdem, Seyfettin
dc.institutionauthorKarahan, Mine
dc.institutionauthorAva, Sedat
dc.institutionauthorDursun, Mehmet Emin
dc.institutionauthorHazar, Leyla
dc.institutionauthorKeklikçi, Uğur
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofGraefe’s Archive for Clinical and Experimental Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectCorneal endotheliumen_US
dc.subjectSpecular microscopyen_US
dc.subjectCell densityen_US
dc.subjectCoefcient of variationen_US
dc.subjectHexagonal cell percentageen_US
dc.titleExamination of the effects of COVID 19 on corneal endotheliumen_US
dc.titleExamination of the effects of COVID 19 on corneal endothelium
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Yükleniyor...
Küçük Resim
İsim:
Examination of the effects of COVID 19 on corneal endothelium.pdf
Boyut:
703.07 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama: