Examination of the effects of COVID 19 on corneal endothelium
Yükleniyor...
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose To demonstrate the efects of the disease on the corneal endothelium in individuals recovering from COVID-19
through specular microscopy.
Methods Eighty individuals recovering from COVID-19 (group 1) and 72 healthy controls (group 2) were included in this
prospective study. After examining visual acuity, refractive defect detection, anterior and posterior segment examinations,
and specular microscopy measurements were calculated from images with at least 100 cells. The mean cell density (CD),
mean coefcient of variation (CV), mean hexagonal cell percentage, mean cell area (AVG), and central corneal thickness
(CCT) were evaluated.
Results The mean time from diagnosis of the disease in group 1 was 54.25±6.36 days. The mean time elapsed since the
PCR test became negative was 38.45±6.87 days. Only four were treated in the hospital. Specular microscopy data showed
that the CD was 2713.56±246.25 and 2845.80±299.27 in groups 1 and 2, respectively (p=0.003). The CV values were
42.92±6.79 and 40.16±5.97, respectively (p=0.009). The hexagonality were 46.51±7.35 and 49.12±6.87, respectively
(p=0.024). The AVG was 371.60±34.64 and 353.16±35.29, respectively (p=0.007). The CCT values were 553.00±73.2,
and 526.84±33.57, respectively (p=0.005).
Conclusion A decrease in the number of endothelial cells and hexagonal cells (polymorphism) as well as an increase in
the cell area change coefcient (polymegatism) and the average cell area were observed from corneal specular microscopic
examination of individuals recovering from COVID-19 in the early period of the disease. These results may be important in
understanding the systemic efects of the disease
Açıklama
WOS:000658679800005
PMID: 34097111
PMID: 34097111
Anahtar Kelimeler
COVID-19, Corneal endothelium, Specular microscopy, Cell density, Coefcient of variation, Hexagonal cell percentage
Kaynak
Graefe’s Archive for Clinical and Experimental Ophthalmology
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
Early Access
Sayı
Künye
Erdem, S., Karahan, M., Ava, S., Dursun, M.E., Hazar, L. ve Keklikçi, U. (2021). Examination of the effects of COVID 19 on corneal endothelium. Graefe’s Archive for Clinical and Experimental Ophthalmology, Early access.
