Evaluation of optimal gastric mucosal biopsy site and number for identification of Helicobacter pylori, gastric atrophy and intestinal metaplasia

Basit Öğe Kaydı
dc.contributor.authorDursun, M
dc.contributor.authorYilmaz, S
dc.contributor.authorYükselen, V
dc.contributor.authorKilinç, N
dc.contributor.authorCanoruç, F
dc.contributor.authorTuzcu, A
dc.date.accessioned2024-04-24T17:33:52Z
dc.date.available2024-04-24T17:33:52Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground/Aims: The study is designed to identify the optimal gastric mucosal biopsy site and number for identification of Helicobacter pylori, gastric atrophy and intestinal metaplasia. Methodology: Ninety-two patients were included in the study, gastric biopsies were obtained from 5 different sites: lesser curvature of the mid-antrum (A(1)), greater curvature of the mid-antrum (A(2)), incisura angularis (IA), lesser curvature of the mid-corpus (B-1), greater curvature of the mid-corpus (B-2). Helicobacter pylori was evaluated in sections stained with toluidine blue, and histopathological. examination was performed in sections stained with hematoxylineosin. Results: Seventy-three patients were positive for Helicobacter pylori at least in one biopsy site. Helicobacter pylori was positive in 47 patients (64.3%) in A(1), in 54 patients (73.9%) in A(2), in 60 patients (82.1%) in IA, 44 patients (60.2%) in B-1, and in 42 patients (57.5%) in B-2. The highest positivity determined was in the combination of A(2) and IA sites (95.8%). Gastric atrophy was determined in 35 of 73 patients (27.1% in A(1), 20% in A(2),25.7% in IA, 20% in B-1, and 7% in B-2). Intestinal metaplasia was determined in B-1 of the Helicobacter pylori-positive patients (18% in A(1), 16% in A(2), 30.9% in IA, 21.8% in B-1, 12.7% in B-2). Conclusions: It is considered that taking biopsies from both A(1) and IA sites has the highest sensitivity in detecting Helicobacter pylori. However, it is difficult to define a specific site for detecting gastric atrophy and intestinal metaplasia.en_US
dc.identifier.endpage1735en_US
dc.identifier.issn0172-6390
dc.identifier.issue60en_US
dc.identifier.pmid15532815
dc.identifier.scopus2-s2.0-6344226058
dc.identifier.scopusqualityN/A
dc.identifier.startpage1732en_US
dc.identifier.urihttps://hdl.handle.net/11468/20869
dc.identifier.volume51en_US
dc.identifier.wosWOS:000224607400036
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherH G E Update Medical Publishing S Aen_US
dc.relation.ispartofHepato-Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHelicobacter Pylorien_US
dc.subjectAtrophyen_US
dc.subjectIntestinal Metaplasiaen_US
dc.titleEvaluation of optimal gastric mucosal biopsy site and number for identification of Helicobacter pylori, gastric atrophy and intestinal metaplasiaen_US
dc.titleEvaluation of optimal gastric mucosal biopsy site and number for identification of Helicobacter pylori, gastric atrophy and intestinal metaplasia
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu