Histopathological assessment of the prophylactic effect of gingko-biloba extract on intestinal ischemia-reperfusion injury

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dc.contributor.authorÖnen, A
dc.contributor.authorDeveci, E
dc.contributor.authorInalöz, SS
dc.contributor.authorIsik, B
dc.contributor.authorKilinc, M
dc.date.accessioned2024-04-24T17:37:30Z
dc.date.available2024-04-24T17:37:30Z
dc.date.issued1999
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn this experimental study, the prophylactic effects of Gingko-Biloba Extract (GBE) were examined after experimental ischemia on intestinal wall damage. 50 Wistar-Albino rats (2.5 month old) were gathered and separated into 5 groups (n:10), Group 1 was subjected to a laparotomy (sham-operated group) whereas all other experimental groups were subjected to an occlusion of their superior mesenteric arteries for 30 minutes and a period of 20 minutes reperfusion following occlusion. Group 2 was not given any prophylactic agent during the experiment (untreated control group). GEE was administered in a dosage of 50 mg/kg (i.v.) as a prophylactic agent to Group 3 one hour prior to laparotomy whereas Group 4 was given GEE at 50 mg/kg (i.v.) just before ischemia, Group 5 was given GEE in the same dosage just before reperfusion, Immediately after reperfusion, a biopsy was taken from the ileum (10 cm proximity to ileocaecal valve) for histopathological assessment. A significant prophylactic effect of GEE was observed in Group 5 in which GEE was administered just before reperfusion.en_US
dc.identifier.endpage389en_US
dc.identifier.issn1784-3227
dc.identifier.issue4en_US
dc.identifier.pmid10692767
dc.identifier.scopus2-s2.0-0342514586
dc.identifier.scopusqualityQ3
dc.identifier.startpage386en_US
dc.identifier.urihttps://hdl.handle.net/11468/20963
dc.identifier.volume62en_US
dc.identifier.wosWOS:000085584100002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherUniv Catholique Louvain-Uclen_US
dc.relation.ispartofActa Gastro-Enterologica Belgica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleHistopathological assessment of the prophylactic effect of gingko-biloba extract on intestinal ischemia-reperfusion injuryen_US
dc.titleHistopathological assessment of the prophylactic effect of gingko-biloba extract on intestinal ischemia-reperfusion injury
dc.typeArticleen_US

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